Shared Risk Factors for Depressive Disorder Among Older Adult Couples in Korea

Although couples may share many risk factors for depressive disorders in their lifetime, whether these factors mediate the shared risk of depressive disorders has rarely been investigated. To identify the shared risk factors for depressive disorder in couples and investigate their mediating roles in...

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Published in:JAMA network open 2023-04, Vol.6 (4), p.e238263-e238263
Main Authors: Han, Ji Won, Yang, Hee Won, Bae, Jong Bin, Oh, Dae Jong, Moon, Dong Gyu, Lim, Eunji, Shin, Jin, Kim, Bong Jo, Lee, Dong Woo, Kim, Jeong Lan, Jhoo, Jin Hyeong, Park, Joon Hyuk, Lee, Jung Jae, Kwak, Kyung Phil, Lee, Seok Bum, Moon, Seok Woo, Ryu, Seung-Ho, Kim, Shin Gyeom, Kim, Ki Woong
Format: Article
Language:English
Subjects:
Adults
Aged
Chronic illnesses
Cohort Studies
Couples
Depressive Disorder - epidemiology
Female
Humans
Longitudinal Studies
Male
Older people
Online Only
Original Investigation
Psychiatry
Republic of Korea - epidemiology
Risk Factors
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Summary:Although couples may share many risk factors for depressive disorders in their lifetime, whether these factors mediate the shared risk of depressive disorders has rarely been investigated. To identify the shared risk factors for depressive disorder in couples and investigate their mediating roles in the shared risk of depressive disorders among older adult couples. This nationwide, multicenter, community-based cohort study assessed 956 older adults from the Korean Longitudinal Study on Cognitive Aging and Dementia (KLOSCAD) and a cohort of their spouses (KLOSCAD-S) between January 1, 2019, to February 28, 2021. Depressive disorders of the KLOSCAD participants. The mediating roles of shared factors in couples on the association between one spouse's depressive disorder and the other's risk of depressive disorders was examined using structural equation modeling. A total of 956 KLOSCAD participants (385 women [40.3%] and 571 men [59.7%]; mean [SD] age, 75.1 [5.0] years) and their spouses (571 women [59.7%] and 385 men [40.3%]; mean [SD] age, 73.9 [6.1] years) were included. The depressive disorders of the KLOSCAD participants were associated with an almost 4-fold higher risk of depressive disorders in their spouses in the KLOSCAD-S cohort (odds ratio, 3.89; 95% CI, 2.06-7.19; P 
ISSN:2574-3805
2574-3805
DOI:10.1001/jamanetworkopen.2023.8263