Perioperative Management of Lewis-Sumner Syndrome

Lewis-Sumner syndrome (LSS) is a rare immune-mediated neuromuscular disorder. It shares some clinical and pathological features with chronic inflammatory demyelinating polyneuropathy (CIDP). We report on the anaesthetic management of a patient with LSS. There are several concerns when anaesthetizing...

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Published in:Curēus (Palo Alto, CA) CA), 2023-03, Vol.15 (3), p.e36297
Main Authors: Sales, Filipa, Cruz, Ana Raquel S, Maldonado, Filipa, Cunha, Mariana
Format: Article
Language:English
Subjects:
Anesthesiology
General anesthesia
Guillain-Barre syndrome
Hemoglobin
Hyperkalemia
Intubation
Medical personnel
Muscle strength
Neurology
Oxygen saturation
Patients
Postoperative period
Regional anesthesia
Surgery
Ventilation
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description Lewis-Sumner syndrome (LSS) is a rare immune-mediated neuromuscular disorder. It shares some clinical and pathological features with chronic inflammatory demyelinating polyneuropathy (CIDP). We report on the anaesthetic management of a patient with LSS. There are several concerns when anaesthetizing patients with demyelinating neuropathies, the main ones being the post-operative worsening of symptoms and respiratory depression related to muscle relaxants. In our experience, the rocuronium effect was prolonged and an even lower dosage (0.4 mg/kg) was sufficient for intubation and maintenance. Sugammadex allowed total reversion of neuromuscular block and no respiratory complications occurred. In conclusion, the combination of lower dose rocuronium and sugammadex was safely used in a patient with LSS.
doi_str_mv 10.7759/cureus.36297
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subjects Anesthesiology
General anesthesia
Guillain-Barre syndrome
Hemoglobin
Hyperkalemia
Intubation
Medical personnel
Muscle strength
Neurology
Oxygen saturation
Patients
Postoperative period
Regional anesthesia
Surgery
Ventilation
title Perioperative Management of Lewis-Sumner Syndrome
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