Meiosis in two human reciprocal translocations

Analysis of meiotic chromosomes from two human male translocation heterozygotes is reported. One had total sterility after maturation arrest and chain configurations at meiosis, and the second had a abnormal children who were presumed to be genetically unbalanced.

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Bibliographic Details
Published in:Journal of medical genetics 1979-02, Vol.16 (1), p.56-59
Main Authors: Román, C S, Sordo, M T, García-Sagredo, J M
Format: Article
Language:English
Subjects:
Abnormalities, Multiple - genetics
Adult
Chromosomes, Human, 1-3
Chromosomes, Human, 6-12 and X
Heterozygote
Humans
Infertility, Male - genetics
Male
Meiosis
Translocation, Genetic
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Description
Summary:Analysis of meiotic chromosomes from two human male translocation heterozygotes is reported. One had total sterility after maturation arrest and chain configurations at meiosis, and the second had a abnormal children who were presumed to be genetically unbalanced.
ISSN:0022-2593
1468-6244
1468-6244
DOI:10.1136/jmg.16.1.56