Frailty and Cardiovascular Mortality: A Narrative Review

Purpose of Review The goal of the narrative review is to provide an overview of the epidemiology of frailty in cardiovascular disease and cardiovascular mortality and discuss applications of frailty in cardiovascular care of older adults. Recent Findings Frailty is highly prevalent in older adults w...

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Bibliographic Details
Published in:Current cardiology reports 2023-04, Vol.25 (4), p.249-259
Main Authors: Ko, Darae, Bostrom, John A., Qazi, Saadia, Kramer, Daniel B., Kim, Dae Hyun, Orkaby, Ariela R.
Format: Article
Language:English
Subjects:
Aged
Cardiology
Cardiovascular Diseases
Frail Elderly
Frailty - epidemiology
Humans
Ischemic Heart Disease (D Mukherjee
Medicine
Medicine & Public Health
Section Editor
Topical Collection on Ischemic Heart Disease
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Summary:Purpose of Review The goal of the narrative review is to provide an overview of the epidemiology of frailty in cardiovascular disease and cardiovascular mortality and discuss applications of frailty in cardiovascular care of older adults. Recent Findings Frailty is highly prevalent in older adults with cardiovascular disease and is a robust, independent predictor of cardiovascular death. There is a growing interest in using frailty to inform management of cardiovascular disease either through pre- or post-treatment prognostication or by delineating treatment heterogeneity in which frailty serves to distinguish patients with differential harms or benefits from a given therapy. Summary Frailty can enable more individualized treatment in older adults with cardiovascular disease. Future studies are needed to standardize frailty assessment across cardiovascular trials and enable implementation of frailty assessment in cardiovascular clinical practice.
ISSN:1523-3782
1534-3170
DOI:10.1007/s11886-023-01847-0