Birth distribution in cystic fibrosis in Saguenay-Lac-St-Jean, Quebec, Canada

Although a seasonal trend in the birth distribution has been reported in cystic fibrosis (CF), this finding is still very controversial. The birth distribution of 113 patients with cystic fibrosis born in Saguenay-Lac-St-Jean (complete ascertainment) was analysed using two different statistical meth...

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Bibliographic Details
Published in:Journal of medical genetics 1991-09, Vol.28 (9), p.613-614
Main Authors: Daigneault, J, Aubin, G, Simard, F, De Braekeleer, M
Format: Article
Language:English
Subjects:
Biological and medical sciences
birth
Cystic Fibrosis - epidemiology
Cystic Fibrosis - ethnology
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Infant, Newborn
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Medical sciences
Monte Carlo Method
Other diseases. Semiology
Quebec - epidemiology
Seasons
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Summary:Although a seasonal trend in the birth distribution has been reported in cystic fibrosis (CF), this finding is still very controversial. The birth distribution of 113 patients with cystic fibrosis born in Saguenay-Lac-St-Jean (complete ascertainment) was analysed using two different statistical methods. Our results showed no monthly or seasonal birth variation. It is likely that a bias owing to incomplete ascertainment might explain why some previous studies found a seasonal trend in the birth distribution of cystic fibrosis.
ISSN:0022-2593
1468-6244
1468-6244
DOI:10.1136/jmg.28.9.613