Role of phytocompounds as the potential anti-viral agent: an overview

Viral diseases are the most notorious infective agent(s) causing morbidity and mortality in every nook and corner for ages; viruses are active in host cells, and specific anti-virus medicines’ developments remain uncanny. In this century of the biological era, human viruses act predominantly as vers...

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Bibliographic Details
Published in:Naunyn-Schmiedeberg's archives of pharmacology 2023-10, Vol.396 (10), p.2311-2329
Main Authors: Mohanty, Swati Sucharita, Sahoo, Chita Ranjan, Paidesetty, Sudhir Kumar, Padhy, Rabindra Nath
Format: Article
Language:English
Subjects:
Antiviral activity
Antiviral agents
Biomedical and Life Sciences
Biomedicine
COVID-19
Flavonoids
Integument
Morbidity
Natural products
Neurosciences
Pharmacology/Toxicology
Polysaccharides
Review
Saponins
Therapeutic applications
Viral infections
Viruses
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Summary:Viral diseases are the most notorious infective agent(s) causing morbidity and mortality in every nook and corner for ages; viruses are active in host cells, and specific anti-virus medicines’ developments remain uncanny. In this century of the biological era, human viruses act predominantly as versatile spreaders. The infection of the present COVID-19 virus is up in the air; blithely, the integument of medicinal chemistry approaches, particularly bioactive derived phytocompounds could be helpful to control those human viruses, recognized in the last 100 years. Indeed, natural products are being used for various therapeutic purposes. The major bioactive phytocompounds are chemically containing coumarin, thiosulfonate, steroid, polysaccharide, tannin, lignin, proanthocyanidin, terpene, quinone, saponin, flavonoid, alkaloid, and polyphenol, that are documented for inhibitory action against several viral infections. Mostly, about 20–30% of plants from tropical or temperate regions are known to have some antiviral activity. This comprehensive analysis of bioactive-derived phytocompounds would represent a significant impact and might be helpful for antiviral research and the current state of viral treatments.
ISSN:0028-1298
1432-1912
DOI:10.1007/s00210-023-02517-2