Clinical Significance of the Prealbumin Level in Gastric Cancer Patients Who Receive Curative Treatment

Background We investigated the clinical influence of the prealbumin level on the gastric cancer survival and recurrence after curative treatment. Methods This study included 447 patients who underwent curative treatment for gastric cancer between 2013 and 2017. The risk factors for the overall survi...

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Bibliographic Details
Published in:Journal of gastrointestinal cancer 2023-03, Vol.54 (1), p.27-34
Main Authors: Aoyama, Toru, Nakazono, Masato, Segami, Kenki, Nagasawa, Shinsuke, Kano, Kazuki, Hara, Kentaro, Maezawa, Yukio, Hashimoto, Itaru, Suematsu, Hideaki, Watanabe, Hayato, Komori, Keisuke, Tamagawa, Hiroshi, Yukawa, Norio, Rino, Yasushi, Ogata, Takashi, Oshima, Takashi
Format: Article
Language:English
Subjects:
Cancer Research
Clinical Relevance
Gastroenterology
Humans
Internal Medicine
Lymph Nodes
Medicine
Medicine & Public Health
Neoplasm Recurrence, Local - epidemiology
Oncology
Original Research
Prealbumin
Prognosis
Radiotherapy
Retrospective Studies
Risk Factors
Stomach Neoplasms - surgery
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Summary:Background We investigated the clinical influence of the prealbumin level on the gastric cancer survival and recurrence after curative treatment. Methods This study included 447 patients who underwent curative treatment for gastric cancer between 2013 and 2017. The risk factors for the overall survival (OS) and recurrence-free survival (RFS) were identified. Results A prealbumin level of 20 mg/dl was regarded as the optimal point of classification, considering the 3- and 5-year survival rates. The OS rates at 3 and 5 years after surgery were 80.7% and 65.0% in the low-prealbumin group, respectively, and 93.1% and 87.9% in the high-prealbumin group, respectively, a statistically significant difference ( p  
ISSN:1941-6628
1941-6636
DOI:10.1007/s12029-021-00777-w