The influence of calcium silicate-based cement on osseous healing: A systematic review and meta-analysis

Objectives: The purpose of this systematic review was to analyze the effect of commercially available calcium silicate-based bioactive endodontic cement (BEC) on treatment outcome when used as root repair material in human permanent teeth and to compare it with traditional materials. Methods: PubMed...

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Bibliographic Details
Published in:Journal of conservative dentistry 2023-03, Vol.26 (2), p.122-133
Main Authors: Nawal, Ruchika, Yadav, Sudha, Talwar, Sangeeta, Malhotra, Rajeev, Pruthi, Preeti, Goel, Shruti, Malik, Reema, Shailat, Mayank
Format: Article
Language:English
Subjects:
Analysis
Clinical outcomes
Dental cement
Medical research
Medicine, Experimental
Meta-analysis
Quality control
Review
Reviews
Systematic review
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Summary:Objectives: The purpose of this systematic review was to analyze the effect of commercially available calcium silicate-based bioactive endodontic cement (BEC) on treatment outcome when used as root repair material in human permanent teeth and to compare it with traditional materials. Methods: PubMed, Embase, and Cochrane Library were searched until June 2020. Randomized clinical studies and observational studies with a minimum 1-year follow-up and sample size of at least 20 were included. Risk of bias (ROB) was assessed using Cochrane's ROB tool and the National Institutes of Health Quality Assessment Tool. Results: Thirty-nine studies were included in the systematic review. Majority of the studies used mineral trioxide aggregate. The pooled success rate for BEC was estimated by a random-effects method as 90.49% (95% confidence interval [CI]: 88.4992.34, I2 = 54%). Eleven studies comparing BEC with traditional materials were included in the meta-analysis. The use of BEC significantly improved the treatment outcome when compared to traditional materials with odds ratio (OR) = 2.15 (95% CI: 1.57-2.96, I2 = 0.8%, P = 0.433). Conclusion: Very low-to-moderate-quality evidence suggests that the use of BEC as root repair material enhanced the treatment outcome. High-quality studies are required for the newer BEC to establish their clinical performance. Registration: PROSPERO CRD42020211502.
ISSN:0972-0707
0974-5203
DOI:10.4103/jcd.jcd_498_22