Association between a rapid diagnostic test to detect methicillin-resistant Staphylococcus Aureus pneumonia and decreased vancomycin use in a medical intensive care unit over a 30-month period

Vancomycin overuse is common, yet few data are available regarding how to improve stewardship of this antibiotic. We identify an association between use of a PCR assay to rule out MRSA pneumonia and a significant, sustained decrease in average vancomycin days of therapy over a 30-month period.

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Bibliographic Details
Published in:Infection control and hospital epidemiology 2021-11, Vol.42 (11), p.1385-1387
Main Authors: Pickens, Chiagozie I, Qi, Chao, Postelnick, Michael, Paonessa, Joseph, Donnelly, Helen K, Wunderink, Richard G
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - therapeutic use
Antibiotics
Clinical trials
Diagnostic tests
Diagnostic Tests, Routine
Humans
Intensive care
Intensive Care Units
Kidneys
Medical diagnosis
Methicillin-Resistant Staphylococcus aureus
Mortality
Pneumonia
Pneumonia, Staphylococcal - diagnosis
Pneumonia, Staphylococcal - drug therapy
Retrospective Studies
Staphylococcal Infections - diagnosis
Staphylococcal Infections - drug therapy
Staphylococcus infections
Trends
Vancomycin - therapeutic use
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Description
Summary:Vancomycin overuse is common, yet few data are available regarding how to improve stewardship of this antibiotic. We identify an association between use of a PCR assay to rule out MRSA pneumonia and a significant, sustained decrease in average vancomycin days of therapy over a 30-month period.
ISSN:0899-823X
1559-6834
DOI:10.1017/ice.2020.1406