Nausea, Vomiting, and Diarrhea Are Common in Community-Acquired Acute Viral Respiratory Illness

Background Gastrointestinal (GI) symptoms are recognized sequelae of acute respiratory illness (ARI), but their prevalence is not well documented. Our study aim was to assess the incidence of GI symptoms in community ARI cases for persons of all ages and their association with clinical outcomes. Met...

Full description

Saved in:
Bibliographic Details
Published in:Digestive diseases and sciences 2023-08, Vol.68 (8), p.3383-3389
Main Authors: Newman, Kira L., Wolf, Caitlin R., Logue, Jennifer K., Englund, Janet A., Boeckh, Michael, Chu, Helen Y.
Format: Article
Language:English
Subjects:
Analysis
Biochemistry
Coronaviruses
Diarrhea
Diarrhea - diagnosis
Diarrhea - epidemiology
Gastroenterology
Gastrointestinal Diseases - diagnosis
Gastrointestinal Diseases - epidemiology
Hepatology
Humans
Infant
Medicine
Medicine & Public Health
Nausea
Oncology
Original
Original Article
Pathogens
Prospective Studies
Respiratory diseases
Respiratory Tract Infections - diagnosis
Respiratory Tract Infections - epidemiology
Surveillance
Transplant Surgery
Virus Diseases - diagnosis
Virus Diseases - epidemiology
Vomiting
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Gastrointestinal (GI) symptoms are recognized sequelae of acute respiratory illness (ARI), but their prevalence is not well documented. Our study aim was to assess the incidence of GI symptoms in community ARI cases for persons of all ages and their association with clinical outcomes. Methods We collected mid-nasal swabs, clinical, and symptom data from Seattle-area individuals during the 2018–2019 winter season as part of a large-scale prospective community surveillance study. Swabs were tested by polymerase chain reaction (PCR) for 26 respiratory pathogens. Likelihood of GI symptoms given demographic, clinical, and microbiological covariates were analyzed with Fisher’s exact, Wilcoxon-rank-sum, and t-tests and multivariable logistic regression. Results In 3183 ARI episodes, 29.4% had GI symptoms (n = 937). GI symptoms were significantly associated with pathogen detection, illness interfering with daily life, seeking care for the illness, and greater symptom burden (all p  3 symptoms, and month, influenza (p 
ISSN:0163-2116
1573-2568
DOI:10.1007/s10620-023-07976-4