Estimated Glucose Disposal Rate Predicts Renal Progression in Type 2 Diabetes Mellitus: A Retrospective Cohort Study

Abstract Context Insulin resistance is a feature of type 2 diabetes mellitus (T2DM). The estimated glucose disposal rate (eGDR), a validated marker for insulin resistance, is associated with complications of diabetes, but few studies have explored the relationship between eGDR and renal outcomes in...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the Endocrine Society 2023-06, Vol.7 (7), p.bvad069-bvad069
Main Authors: Peng, Juan, Li, Aimei, Yin, Liangqingqing, Yang, Qi, Pan, Jinting, Yi, Bin
Format: Article
Language:English
Subjects:
Analysis
Chronic kidney failure
Clinical
Development and progression
Dextrose
Glucose
Glycosylated hemoglobin
Insulin
Insulin resistance
Low density lipoproteins
Medical research
Medicine, Experimental
Prognosis
Risk factors
Type 1 diabetes
Type 2 diabetes
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Context Insulin resistance is a feature of type 2 diabetes mellitus (T2DM). The estimated glucose disposal rate (eGDR), a validated marker for insulin resistance, is associated with complications of diabetes, but few studies have explored the relationship between eGDR and renal outcomes in T2DM. Objective This study investigated the value of eGDR in predicting renal progression in T2DM. Methods A total of 956 T2DM patients with a baseline estimated glomerular filtration rate (eGFR) ≥ 60 mL/min/1.73 m2 and 5 years of follow-up were enrolled. Primary outcomes were rapid eGFR decline, eGFR
ISSN:2472-1972
2472-1972
DOI:10.1210/jendso/bvad069