State of the Art of Genomic Technology in Toxicology: A Review

The rapid growth of genomics techniques has revolutionized and impacted, greatly and positively, the knowledge of toxicology, ushering it into a "new era": the era of genomic technology (GT). This great advance permits us to analyze the whole genome, to know the gene response to toxicants...

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Bibliographic Details
Published in:International journal of molecular sciences 2023-06, Vol.24 (11), p.9618
Main Authors: Recio-Vega, Rogelio, Facio-Campos, Rolando Adair, Hernández-González, Sandra Isabel, Olivas-Calderón, Edgar
Format: Article
Language:English
Subjects:
Analysis
Arsenic
Artificial intelligence
Biomarkers
Bisphenol A
Breast cancer
Chemicals
Disease
DNA methylation
Epigenetics
Fenofibrate
Gene expression
Genes
Genomes
Genomics
Genomics - methods
Hazardous Substances
Humans
Kidney cancer
Medical prognosis
Medical research
Medicine, Experimental
MicroRNAs
Miscarriage
Pollutants
Polycystic ovary syndrome
Pregnancy
Proteomics
Review
Sperm
Toxicants
Toxicity
Toxicology
Toxicology - methods
Womens health
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Summary:The rapid growth of genomics techniques has revolutionized and impacted, greatly and positively, the knowledge of toxicology, ushering it into a "new era": the era of genomic technology (GT). This great advance permits us to analyze the whole genome, to know the gene response to toxicants and environmental stressors, and to determine the specific profiles of gene expression, among many other approaches. The aim of this work was to compile and narrate the recent research on GT during the last 2 years (2020-2022). A literature search was managed using the PubMed and Medscape interfaces on the Medline database. Relevant articles published in peer-reviewed journals were retrieved and their main results and conclusions are mentioned briefly. It is quite important to form a multidisciplinary taskforce on GT with the aim of designing and implementing a comprehensive, collaborative, and a strategic work plan, prioritizing and assessing the most relevant diseases, so as to decrease human morbimortality due to exposure to environmental chemicals and stressors.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms24119618