COVID-19 mortality and risk factors in patients with cancer in Ecuador: A retrospective, non-randomized, controlled study

The 2019 coronavirus disease (COVID-19) pandemic has affected different human populations since March 2020 and challenged healthcare systems, especially in chronic non-communicable diseases such as cancer. The present study aimed to evaluate the mortality, risk factors, and symptoms of cancer patien...

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Bibliographic Details
Published in:Medicine (Baltimore) 2023-06, Vol.102 (25), p.e34082-e34082
Main Authors: Valencia-Espinoza, Evelyn, Cabezas, María del Carmen, Plaza, Andrea, García, Katherine, Calle, Carlos, Fornasini, Marco, Luna, José, Miño, Camila
Format: Article
Language:English
Subjects:
Adult
COVID-19 - epidemiology
COVID-19 Drug Treatment
Ecuador - epidemiology
Ferritins
Humans
Neoplasms - epidemiology
Observational Study
Respiration, Artificial
Retrospective Studies
Risk Factors
SARS-CoV-2
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Summary:The 2019 coronavirus disease (COVID-19) pandemic has affected different human populations since March 2020 and challenged healthcare systems, especially in chronic non-communicable diseases such as cancer. The present study aimed to evaluate the mortality, risk factors, and symptoms of cancer patients and control subjects, diagnosed with COVID-19 and admitted to intensive care unit (ICU). This retrospective, observational, non-randomized, controlled study of patients admitted to ICU was conducted between March and August 2020 in an Ecuadorian oncology center. Patient information collected from electronic medical records included sociodemographic information, clinical history, symptoms, laboratory test results, COVID-19 treatment, and discharge status. For patients with neoplasia, diagnosis, type, and status of cancer, as well as antineoplastic treatment received over the past month was also recorded. Descriptive statistics and multiple logistic regression were used to analyze the data. Statistical analysis was performed with SPSS (version 22.0) and R (version 4.1.3). In total, 79 adult COVID-19 patients were studied (40 with cancer and 39 controls). The total mean time until COVID-19 symptoms onset was 6.2 ± 3.5 days (5.3 ± 3.2 days in the cancer group vs 7.2 ± 3.6 days in the control group; P = .016) but no difference was observed in reported symptoms. All patients received an antibiotic treatment, but only 70% of the cancer group had antivirals (P 
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000034082