Novel vs. modified platelet-rich plasma therapy for hair loss treatment: a systematic review and meta-analysis

Platelet-rich plasma (PRP) therapy, is a stand-alone therapy or is used in combination with other treatments for the treatment of androgenic alopecia. The purpose of this meta-analysis was to compare the improvement in hair density seen, when PRP was used alone and when used as an adjunct. Conformin...

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Bibliographic Details
Published in:Annals of medicine and surgery 2023-06, Vol.85 (6), p.2833-2840
Main Authors: Fatima, Kaneez, Ovais, Haziq, Anwar, Zainab, Abdul Latif Motan, Maaz, Masood Khan, Maaz, Khowaja, Aly H, Shahriyar Ghazanfar, Altamash, Khalid, Muhammad A, Jamil, Ayesha, Ismail Mujtaba, Yahya, Kumar, Sahil, Rashid, Ahmed M
Format: Article
Language:English
Subjects:
Review
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Summary:Platelet-rich plasma (PRP) therapy, is a stand-alone therapy or is used in combination with other treatments for the treatment of androgenic alopecia. The purpose of this meta-analysis was to compare the improvement in hair density seen, when PRP was used alone and when used as an adjunct. Conforming to systematic review and meta-analysis recommendations, we performed a meta-analysis of relevant articles in multiple databases, from inception till May 2022. Randomized clinical trials were included that evaluated the use of PRP alone or used PRP as an adjuvant with previously used therapies. Hair density data at the start of treatment and follow-up after 3 and 6 months was used for analysis. A review of 255 articles included nine studies, for a cumulative data set of 230 individuals. In comparison to the placebo, stand-alone PRP therapy resulted in a significant increase in hair density (MD=25.39,
ISSN:2049-0801
2049-0801
DOI:10.1097/MS9.0000000000000396