Infant feeding, wheezing, and allergy: a prospective study

The determinants of wheezing and allergy were investigated in 453 children with a family history of allergic disease. A randomised controlled trial examined the effects of withholding cows' milk protein during the first three months of life and replacing cows' milk with soya milk. The chil...

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Published in:Archives of disease in childhood 1993-06, Vol.68 (6), p.724-728
Main Authors: Burr, M L, Limb, E S, Maguire, M J, Amarah, L, Eldridge, B A, Layzell, J C, Merrett, T G
Format: Article
Language:English
Subjects:
Allergies
Biological and medical sciences
Breast Feeding
Cattle
Children
Chronic obstructive pulmonary disease, asthma
Cohort Studies
Cow's milk
England - epidemiology
Female
Follow-Up Studies
Genetics
House dust
Humans
Hypersensitivity - diet therapy
Hypersensitivity - epidemiology
Hypersensitivity - etiology
Incidence
Infant
Infant Food
Male
Medical sciences
Milk
Overcrowding
Passive smoking
Peak Expiratory Flow Rate
Pediatrics
Pets
Pneumology
Prevalence
Prospective Studies
Respiratory Sounds - etiology
Respiratory tract infection
Wheezing
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cited_by cdi_FETCH-LOGICAL-b537t-f3af785a0aea3724ea66199c64daad38c39747573f619b08becd045169c5d4673
cites cdi_FETCH-LOGICAL-b537t-f3af785a0aea3724ea66199c64daad38c39747573f619b08becd045169c5d4673
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container_issue 6
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container_title Archives of disease in childhood
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creator Burr, M L
Limb, E S
Maguire, M J
Amarah, L
Eldridge, B A
Layzell, J C
Merrett, T G
description The determinants of wheezing and allergy were investigated in 453 children with a family history of allergic disease. A randomised controlled trial examined the effects of withholding cows' milk protein during the first three months of life and replacing cows' milk with soya milk. The children were followed up to the age of 7 years. Withholding cows' milk did not reduce the incidence of allergy or wheezing. Children who had ever been breast fed had a lower incidence of wheeze than those who had not (59% and 74% respectively). The effect persisted to age 7 years in the non-atopics only, the risk of wheeze being halved in the breast fed children after allowing for employment status, sex passive smoking, and overcrowding. Allergic disease was not associated with exposure to tobacco smoke, house dust mite antigen, or cats. Breast feeding may confer long term protection against respiratory infection.
doi_str_mv 10.1136/adc.68.6.724
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subjects Allergies
Biological and medical sciences
Breast Feeding
Cattle
Children
Chronic obstructive pulmonary disease, asthma
Cohort Studies
Cow's milk
England - epidemiology
Female
Follow-Up Studies
Genetics
House dust
Humans
Hypersensitivity - diet therapy
Hypersensitivity - epidemiology
Hypersensitivity - etiology
Incidence
Infant
Infant Food
Male
Medical sciences
Milk
Overcrowding
Passive smoking
Peak Expiratory Flow Rate
Pediatrics
Pets
Pneumology
Prevalence
Prospective Studies
Respiratory Sounds - etiology
Respiratory tract infection
Wheezing
title Infant feeding, wheezing, and allergy: a prospective study
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