Inhaled nitric oxide for pulmonary hypertension after repair of exomphalos

Inhaled nitric oxide was used successfully to treat a newborn infant with severe pulmonary hypertension complicating repair of congenital exomphalos. The infant had failed conventional treatment and extracorporeal membrane oxygenation was unsuitable because of the risk of bleeding from the recent la...

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Bibliographic Details
Published in:Archives of disease in childhood 1993-11, Vol.69 (5 Spec No), p.518-520
Main Authors: Miller, O I, Gaynor, J W, Macrae, D J, Tasker, R C
Format: Article
Language:English
Subjects:
Administration, Inhalation
Antihypertensive agents
Biological and medical sciences
Cardiovascular system
Hernia, Umbilical - surgery
Humans
Hypertension
Hypertension, Pulmonary - diagnostic imaging
Hypertension, Pulmonary - drug therapy
Hypertension, Pulmonary - etiology
Infant, Newborn
Infants
Male
Medical sciences
Neonates
Nitric oxide
Nitric Oxide - therapeutic use
Oxygenation
Pediatrics
Pharmacology. Drug treatments
Postoperative Complications - drug therapy
Ultrasonography
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Summary:Inhaled nitric oxide was used successfully to treat a newborn infant with severe pulmonary hypertension complicating repair of congenital exomphalos. The infant had failed conventional treatment and extracorporeal membrane oxygenation was unsuitable because of the risk of bleeding from the recent laparotomy. Extended treatment with inhaled nitric oxide appears safe and may offer an alternative to mechanical life support in severe cases of neonatal pulmonary hypertension.
ISSN:0003-9888
1468-2044
DOI:10.1136/adc.69.5_Spec_No.518