COPD Patients with Asthma Features in Vietnam: Prevalence and Suitability for Personalized Medicine

COPD patients with asthma features usually benefit from inhaled corticosteroids (ICS)-containing regimens, but their burden and diagnostic criteria remain to be established. The aims of this study were to estimate the proportion of patients with asthma features among patients with physician-diagnose...

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Bibliographic Details
Published in:Journal of personalized medicine 2023-05, Vol.13 (6), p.901
Main Authors: Van Tho, Nguyen, Phan, Thu Phuong, Dinh-Xuan, Anh Tuan, Ngo, Quy Chau, Lan, Le Thi Tuyet
Format: Article
Language:English
Subjects:
Asthma
Bronchodilators
Care and treatment
Chronic obstructive pulmonary disease
Corticosteroids
Dyspnea
Hospitals
Leukocytes (eosinophilic)
Lung diseases
Medical records
Patients
Physicians
Precision medicine
Quality of life
Spirometry
Tuberculosis
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Summary:COPD patients with asthma features usually benefit from inhaled corticosteroids (ICS)-containing regimens, but their burden and diagnostic criteria remain to be established. The aims of this study were to estimate the proportion of patients with asthma features among patients with physician-diagnosed COPD and to investigate differences in clinical characteristics and current medications between COPD patients with asthma features and patients with COPD alone. A cross-sectional study was conducted at two respiratory out-patient clinics at the University Medical Center in Ho Chi Minh City and Bach Mai Hospital in Ha Noi, Vietnam. COPD patients with asthma features were identified by attending physicians following the approach recommended by the GINA/GOLD joint committee. Of the 332 patients screened, 300 were enrolled in the study. The proportion of COPD patients with asthma features was 27.3% (95% confidence interval (95% CI) 22.6-32.6%). COPD patients with asthma features were younger, with higher FEV values, a greater proportion of positive bronchodilator reversibility tests, higher blood eosinophil count, and were more often treated with ICS/LABA (ICS/long-acting bronchodilator beta-2 agonist) than patients with COPD alone. The prevalence of COPD patients with asthma features is particularly high in Vietnam thus requiring appropriate action plans in clinical practice.
ISSN:2075-4426
2075-4426
DOI:10.3390/jpm13060901