Lipid distributions in the Global Diagnostics Network across five continents

Abstract Aims Lipids are central in the development of cardiovascular disease, and the present study aimed to characterize variation in lipid profiles across different countries to improve understanding of cardiovascular risk and opportunities for risk-reducing interventions. Methods and results Thi...

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Published in:European heart journal 2023-07, Vol.44 (25), p.2305-2318
Main Authors: Martin, Seth S, Niles, Justin K, Kaufman, Harvey W, Awan, Zuhier, Elgaddar, Ola, Choi, Rihwa, Ahn, Sunhyun, Verma, Rajan, Nagarajan, Mahesh, Don-Wauchope, Andrew, Gurgel Castelo, Maria Helane Costa, Hirose, Caio Kenji, James, David, Truman, Derek, Todorovska, Maja, Momirovska, Ana, Pivovarníková, Hedviga, Rákociová, Monika, Louzao-Gudin, Pedro, Batu, Janserey, El Banna, Nehmat, Kapoor, Hema
Format: Article
Language:English
Subjects:
Australia
Austria
Cardiovascular Diseases - diagnosis
Cardiovascular Diseases - epidemiology
Cholesterol, LDL
Clinical Research
Cross-Sectional Studies
Female
Humans
Male
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Summary:Abstract Aims Lipids are central in the development of cardiovascular disease, and the present study aimed to characterize variation in lipid profiles across different countries to improve understanding of cardiovascular risk and opportunities for risk-reducing interventions. Methods and results This first collaborative report of the Global Diagnostics Network (GDN) evaluated lipid distributions from nine laboratory organizations providing clinical laboratory testing in 17 countries on five continents. This cross-sectional study assessed aggregated lipid results from patients aged 20–89 years, tested at GDN laboratories, from 2018 through 2020. In addition to mean levels, the World Health Organization total cholesterol risk target (190 mg/dL) for both females (9.9%) and males (8.7%). LDL-C levels
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/ehad371