Clinico-Demographic Profiles of Herpes Zoster Cases in Patients With and Without COVID-19 Infection During the Pandemic: A Retrospective Analysis of 32 Cases

Coronavirus disease 2019 (COVID-19) has multiple impacts on the human body. The immunological effect is one of the prominent ones, which is thought to be fundamental in many physical manifestations and disease severity. Herpes zoster (HZ) reactivation has been well-linked to immunity; immunocompromi...

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Published in:Curēus (Palo Alto, CA) CA), 2023-06, Vol.15 (6), p.e40063-e40063
Main Authors: Ahmed, Ghazal, Ganguly, Satyaki, Rahim, Jemshi S, George C, Anju, Karim, Habib Md R
Format: Article
Language:English
Subjects:
Abdomen
Coronaviruses
COVID-19 vaccines
Dermatology
Disease
Epidemiology/Public Health
Family/General Practice
Gender
HIV
Human immunodeficiency virus
Immune system
Infections
Pain
Patients
Skin
Software
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Summary:Coronavirus disease 2019 (COVID-19) has multiple impacts on the human body. The immunological effect is one of the prominent ones, which is thought to be fundamental in many physical manifestations and disease severity. Herpes zoster (HZ) reactivation has been well-linked to immunity; immunocompromised states predispose a person to HZ. Studies have raised concerns about HZ incidences in COVID-19 patients; however, the clinical characteristics of the HZ cases among patients with and without COVID-19 are another area to be explored. In this retrospective analysis, we compared the clinical and demographic characteristics of HZ cases presented to our outpatient department immediately before and during the early second wave of the COVID-19 pandemic (September 2020 to April 2021) in India. The cases were divided into two groups based on the history of COVID-19 infections. The clinico-demographic characteristics were then compared using an unpaired t-test, Fisher's exact test, and analysis of variance as applicable using InStat software; a two-sided p-value
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.40063