Causes of late onset epilepsy in Saudi Arabia: the role of cerebral granuloma

Cerebral granulomas, due to infections, have been rarely reported as a cause of late onset epilepsy. The incidence of cerebral granulomas was 7% in this prospective study of 56 consecutive patients with onset of seizures after the age of 20 years. Other main causes included cerebral tumours (20%), a...

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Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1987-01, Vol.50 (1), p.90-92
Main Authors: Yaqub, B A, Panayiotopoulos, C P, Al-Nozha, M, Qteishat, W, Al-Dalaan, A
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Arteriovenous Malformations - complications
Biological and medical sciences
Brain Diseases - complications
Brain Neoplasms - complications
Cerebrovascular Disorders - complications
Epilepsy - ethnology
Epilepsy - etiology
Female
General aspects
Granuloma - complications
Human infectious diseases. Experimental studies and models
Humans
Infectious diseases
Male
Medical sciences
Middle Aged
Nervous system involvement in other diseases. Miscellaneous
Neurology
Saudi Arabia
Tropical medicine
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Summary:Cerebral granulomas, due to infections, have been rarely reported as a cause of late onset epilepsy. The incidence of cerebral granulomas was 7% in this prospective study of 56 consecutive patients with onset of seizures after the age of 20 years. Other main causes included cerebral tumours (20%), arteriovenous malformations (5%) and cerebrovascular disease (15% amongst patients with onset of seizures above the age of 40 years). The incidence of structural abnormalities was higher with increasing age at the onset of seizures and declined with long duration of history of epilepsy. Simple partial seizures were strongly associated with structural abnormalities (86%) as opposed to complex partial (33%) and generalised tonic-clonic seizures (33%).
ISSN:0022-3050
1468-330X
DOI:10.1136/jnnp.50.1.90