The role of oxidant-antioxidant markers and resistin in metabolic syndrome elderly individuals

In elderly, hormones and oxidant-antioxidant interplay are suggested to mediate biochemical balance between adipose tissue to other tissues. Thus the study attempts to explore metabolic traits, plasma resistin, and oxidant-antioxidant markers in metabolic syndrome (MetS) in comparison to non-metabol...

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Bibliographic Details
Published in:Science progress (1916) 2021-04, Vol.104 (2), p.368504211006510
Main Authors: Dzięgielewska-Gęsiak, Sylwia, Wyszomirska, Karolina, Fatyga, Edyta, Wysocka, Ewa, Muc-Wierzgoń, Małgorzata
Format: Article
Language:English
Subjects:
Adipose tissue
Age
Aged
Antioxidants
Biomarkers
Blood pressure
Correlation
Fasting
Glucose
High density lipoprotein
Hormones
Humans
Lipids
Markers
Metabolic disorders
Metabolic syndrome
Metabolic Syndrome - metabolism
Multiple regression analysis
Older people
Oxidants
Oxidative stress
Oxidizing agents
Resistin
Superoxide Dismutase
Thiobarbituric acid
Triglycerides
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Summary:In elderly, hormones and oxidant-antioxidant interplay are suggested to mediate biochemical balance between adipose tissue to other tissues. Thus the study attempts to explore metabolic traits, plasma resistin, and oxidant-antioxidant markers in metabolic syndrome (MetS) in comparison to non-metabolic syndrome (non-MetS) elderly individuals. A total of 541 healthy elderly Caucasians, with no acute and/or chronic disorders were invited. After taking into account inclusion/exclusion criteria’s the MetS was defined as the presence of three out of five abnormal findings and allowed to divided groups into: non-metabolic syndrome, non-MetS (n = 25, median age 69.0 years), and newly diagnosed MetS (n = 29; median age 70.5 years) individuals. Glucose, plasma lipids, resistin (Res), thiobarbituric acid-reacting substances (TBARS), total antioxidant status (TAS), and Cu,Zn-superoxide dismutase (SOD-1) were measured. The MetS had higher resistin than non-MetS (p 
ISSN:0036-8504
2047-7163
DOI:10.1177/00368504211006510