Association between Dietary Habits and Sarcopenia in Patients with Liver Cirrhosis

• Published in: Journal of clinical medicine 2023-07, Vol.12 (14), p.4693
• Main Authors: Topan, Mirabela-Madalina, Sporea, Ioan, Dănilă, Mirela, Popescu, Alina, Ghiuchici, Ana-Maria, Lupușoru, Raluca, Șirli, Roxana
• Format: Article
• Language: English
• Subjects: Ascites; Body mass index; Care and treatment; Clinical medicine; Complications and side effects; Edema; Food; Food habits; Health aspects; Hepatitis; International organizations; Liver cirrhosis; Liver diseases; Methods; Mortality; Muscle strength; Musculoskeletal system; Normal distribution; Nutrition; Nutrition research; Nutritional status; Obesity; Patient compliance; Patients; Prevention; Product/Service Evaluations; Proteins; Risk factors; Sarcopenia; Software; Statistical analysis
• ISSN: 2077-0383; 2077-0383
• DOI: 10.3390/jcm12144693

Sarcopenia and sarcopenic obesity are frequent complications of cirrhosis, and the dietary patterns of patients with these diseases significantly impact the development of both conditions. This study aims to evaluate the adequacy of the dietary intake of patients with liver cirrhosis. A total of 201 patients with liver cirrhosis were included in this analysis. We evaluated the nutritional status of the patients as stated by EWGSOP2 criteria. Subjects were divided into three groups: non-sarcopenic, sarcopenic, and with sarcopenic obesity. We conducted a dietary assessment three times over nonconsecutive 24 h periods within a month. According to EWGSOP2 criteria, combining low handgrip strength with low skeletal muscle index, the prevalence of sarcopenia was 57.2%. Sarcopenic obesity was found in 25.3% of patients. In the sarcopenic group of patients, the energy intake was lower than the current recommendations. Regarding protein intake, the consumption was relatively low in both sarcopenia and sarcopenic obesity samples of patients (0.85 g/kg body weight and 0.77 g/kg BW, < 0.0001). Patients had a median of 2-3 eating episodes daily, and they often missed late-evening snacks. In conclusion, diet quality in cirrhotic patients was relatively poor, and energy and protein intakes were lower than suggested.