Association of follicle‐stimulating hormone with bone turnover markers and bone mineral density in Chinese women across the menopausal transition

Background Elevated follicle‐stimulating hormone (FSH) is associated with an increased risk of postmenopausal osteoporosis. This study investigated the association of serum FSH with bone turnover markers (BTMs) and bone mineral density (BMD) in healthy women undergoing menopausal transition. Methods...

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Bibliographic Details
Published in:Journal of clinical laboratory analysis 2023-05, Vol.37 (9-10), p.e24899-n/a
Main Authors: Li, Lin, Pi, Yin‐Zhen, Zhang, Hong, Dai, Ru‐Chun, Yuan, Ling‐Qing, Sheng, Zhi‐Feng, Wu, Xi‐Yu
Format: Article
Language:English
Subjects:
Age
Alkaline phosphatase
Blood diseases
Body mass index
Bone density
Bone mineral density
Bone turnover
bone turnover markers
Chinese women
Collagen
Collagen (type I)
Estrogens
Follicle-stimulating hormone
Follicles
Fractures
Health care
Hip
Laboratories
Longitudinal studies
menopausal transition
Menopause
Menstruation
Metabolism
Osteocalcin
Osteoporosis
Post-menopause
Risk factors
Spine (lumbar)
Thyroid gland
Womens health
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Summary:Background Elevated follicle‐stimulating hormone (FSH) is associated with an increased risk of postmenopausal osteoporosis. This study investigated the association of serum FSH with bone turnover markers (BTMs) and bone mineral density (BMD) in healthy women undergoing menopausal transition. Methods A total of 487 healthy women (age 35–65 years, 50 ± 8.5 years) were enrolled in this study. Serum FSH, BTMs, and BMD at lumbar spine and total hip were measured in these subjects. Results Follicle‐stimulating hormone was positively correlated with various BTMs (r = 0.339–0.583, all p 
ISSN:0887-8013
1098-2825
DOI:10.1002/jcla.24899