Nuclear cataract and myopia during hyperbaric oxygen therapy

The effect on the human lens of prolonged hyperbaric oxygen therapy is reported. Eye examinations were given to 25 patients before, during, and after a series of 150 or more exposures to hyperbaric oxygen. All patients changed refraction in the direction of myopia during treatment. Fifteen of the pa...

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Bibliographic Details
Published in:British journal of ophthalmology 1984-02, Vol.68 (2), p.113-117
Main Authors: Palmquist, B. M., Philipson, B., Barr, P. O.
Format: Article
Language:English
Subjects:
Adult
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Cataract - etiology
Emergency and intensive care: techniques, logistics
Female
Humans
Hyperbaric Oxygenation - adverse effects
Intensive care medicine
Lens Nucleus, Crystalline
Male
Medical sciences
Middle Aged
Myopia - etiology
Perfusions. Catheterizations. Hyperbaric oxygenotherapy
Refraction, Ocular
Time Factors
Visual Acuity
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Summary:The effect on the human lens of prolonged hyperbaric oxygen therapy is reported. Eye examinations were given to 25 patients before, during, and after a series of 150 or more exposures to hyperbaric oxygen. All patients changed refraction in the direction of myopia during treatment. Fifteen of the patients had clear lens nuclei before treatment. Seven of these developed a nuclear cataract with reduced visual acuity during treatment. Reversible lens myopia has previously been noticed as a side effect of exposure to hyperbaric oxygen, but the cataractogenic effect in man has not been reported by other workers. This report strongly supports the theory of an oxidative damage to the lens proteins as a cause of nuclear cataract.
ISSN:0007-1161
1468-2079
DOI:10.1136/bjo.68.2.113