Paraplegia as a Rare Clinical Presentation of Relapsed Acute Myeloid Leukemia

Myeloid sarcoma, also known as granulocytic sarcoma or chloroma, is an extra-medullary accumulation of malignant myeloid blast cells, leading to a solid tumor formation. Herein, we report a rare presentation of a case with acute myeloid leukemia (AML), whose disease relapse was clinically evident as...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2023-07, Vol.15 (7), p.e41421
Main Authors: Osman, Haitham, Gism Elseed, Israa, Hussein, Sheikheldein B, Mando, Naima, Alraheili, Alaa A
Format: Article
Language:English
Subjects:
Bone marrow
Case reports
Chemotherapy
Emergency medical care
Epidural
Granulomas
Hematology
Histopathology
Hospitals
Internal Medicine
Leukemia
Leukocytes
Lymphatic system
Magnetic resonance imaging
Military reserves
Morphology
Mutation
Oncology
Paralysis
Sarcoma
Tuberculosis
Tumors
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Description
Summary:Myeloid sarcoma, also known as granulocytic sarcoma or chloroma, is an extra-medullary accumulation of malignant myeloid blast cells, leading to a solid tumor formation. Herein, we report a rare presentation of a case with acute myeloid leukemia (AML), whose disease relapse was clinically evident as acute flaccid paraplegia with a certain sensory level. On thoracic spine magnetic resonance imaging (MRI), an epidural mass compressing the spinal cord at the level of the thoracic spine segment 4 (T4) was found. The mass histology confirmed the diagnosis of myeloid sarcoma.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.41421