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Primary Parotid Angiosarcoma in a 66-year-old Man Initially Presented as Cervical Lymph Node Metastasis: Pitfall Diagnosis with Review of Literature
Angiosarcoma is a malignant vascular tumor that occurs mostly in the soft tissues, skin, trunk, and limbs. Angiosarcoma of the parotid gland is a very uncommon and rare tumor. Herein, we presented a case of a 66-year-old man who was referred for a lump in his neck and his initial biopsy reported Cas...
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Published in: | Iranian journal of pathology 2023-04, Vol.18 (2), p.225-228 |
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Main Authors: | , , , |
Format: | Article |
Language: | English |
Subjects: | |
Online Access: | Get full text |
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Summary: | Angiosarcoma is a malignant vascular tumor that occurs mostly in the soft tissues, skin, trunk, and limbs. Angiosarcoma of the parotid gland is a very uncommon and rare tumor.
Herein, we presented a case of a 66-year-old man who was referred for a lump in his neck and his initial biopsy reported Castleman disease. After three months during which the mass did not resolve, a re-biopsy was performed. The biopsy revealed vascular neoplasm composed of neoplastic spindle cells arranged in fascicles with extravasation of the red blood cells within the lymph node. A diagnosis of metastatic angiosarcoma was confirmed by immunohistochemical staining. The neoplastic cells were positive for vimentin, EMA, and CD31. The patient underwent radiation therapy. Nine months later, MRI (magnetic resonance imaging) showed a tumor in the parotid gland. The microscopic examination revealed a primary angiosarcoma of the parotid. Although primary angiosarcoma of the parotid gland is very rare, it should be considered as a possible origin in metastatic angiosarcoma of the neck. Further studies are recommended to more cleary define the process. |
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ISSN: | 1735-5303 2345-3656 |
DOI: | 10.30699/IJP.2023.1971484.2998 |