Chlamydial infection of the male baboon urethra

Two adult male baboons (Papio cynocephalus) were infected by urethral catheter with a Type D strain of Chlamydia trachomatis isolated from a male patient with nongonococcal urethritis. Chlamydial organisms were shed from the urethra for about 90 days and serum antibody developed. Intraurethral re-in...

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Bibliographic Details
Published in:British journal of venereal diseases 1975-10, Vol.51 (5), p.310-313
Main Authors: Digiacomo, R F, Gale, J L, Wang, S P, Kiviat, M D
Format: Article
Language:English
Subjects:
Animals
Antibodies, Bacterial - analysis
Chlamydia Infections - immunology
Chlamydia Infections - microbiology
Chlamydia trachomatis - immunology
Chlamydia trachomatis - isolation & purification
Haplorhini
Humans
Male
Papio
Urethra - microbiology
Urethritis - immunology
Urethritis - microbiology
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Summary:Two adult male baboons (Papio cynocephalus) were infected by urethral catheter with a Type D strain of Chlamydia trachomatis isolated from a male patient with nongonococcal urethritis. Chlamydial organisms were shed from the urethra for about 90 days and serum antibody developed. Intraurethral re-inoculation of homologous and heterologous (Type I) strains of Chalmydia, 4 and 11 months later, resulted in relatively shorter periods of infection of less than 15 days. The antibody titres and type-specific patterns were not substantially influenced by re-infection.
ISSN:0007-134X
1368-4973
1472-3263
DOI:10.1136/sti.51.5.310