Sexual transmission of hepatitis B surface antigen. Infection of husbands by HBsAg carrier-state wives

The husbands of 68 hepatitis B surface antigen (HBsAg) carrier-state wives were tested for the presence of hepatitis B surface antibody (HBsAb) and antigen (HBsAg) to assess possible transmission of HBsAg. Eight (11.8%) of the 68 husbands gave negative results for HBsAg and 22 (32.4%) positive resul...

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Bibliographic Details
Published in:British journal of venereal diseases 1979-10, Vol.55 (5), p.366-368
Main Authors: Inaba, N, Ohkawa, R, Matsuura, A, Kudoh, J, Takamizawa, H
Format: Article
Language:English
Subjects:
Carrier State - immunology
Female
Hepatitis B
Hepatitis B - immunology
Hepatitis B - transmission
Hepatitis B Antibodies - analysis
Hepatitis B Surface Antigens - analysis
Humans
Male
Pregnancy
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Summary:The husbands of 68 hepatitis B surface antigen (HBsAg) carrier-state wives were tested for the presence of hepatitis B surface antibody (HBsAb) and antigen (HBsAg) to assess possible transmission of HBsAg. Eight (11.8%) of the 68 husbands gave negative results for HBsAg and 22 (32.4%) positive results for HBsAb. Furthermore, eight (26.7%) of 30 husbands with presumed HBsAg transmission from their wives developed acute viral hepatitis after marriage, and e antigen (eAg) was detected in the serum from all eight wives. Although HbsAg was not detected in specimens of sputum and cervical mucus of carrier-state women by reverse passive haemagglutination, it was detected in the vaginal discharge of women during days 1--6 of the menstrual cycle at a rate ranging from 20--60%. Thus, sexual transmission of HBsAg seems to occur, particularly if sexual contact takes place during or immediately after menstruation.
ISSN:0007-134X
1368-4973
1472-3263
DOI:10.1136/sti.55.5.366