Structural Characteristics and Properties of Redissolved Silk Sericin

Silk sericin has garnered the attention of researchers as a promising biomaterial because of its good biocompatibility and high water retention. However, despite its useful properties, the poor storage stability of sericin has restricted its extensive use in biorelated applications. This study extra...

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Bibliographic Details
Published in:Polymers 2023-08, Vol.15 (16), p.3405
Main Authors: Lee, Hye Gyeoung, Jang, Mi Jin, Park, Byung-Dae, Um, In Chul
Format: Article
Language:English
Subjects:
Acids
Analysis
Aqueous solutions
Biocompatibility
Biological products
Biomedical materials
Cytotoxicity
Dissolution
Pore size
Silk
Silkworms
Storage stability
Temperature
Thermal decomposition
Viscosity
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Summary:Silk sericin has garnered the attention of researchers as a promising biomaterial because of its good biocompatibility and high water retention. However, despite its useful properties, the poor storage stability of sericin has restricted its extensive use in biorelated applications. This study extracted sericin from silkworm cocoon, dried and stored it as a solid, and then dissolved it in hot water conditions to improve the storage stability of sericin for its use. The dissolution behavior of the extracted sericin solids was examined in conjunction with the structural characteristics and properties of dissolved sericin. Consequently, the results of solution viscosity, gel strength, crystallinity index, and thermal decomposition temperature indicated that the molecular weight (MW) of the dissolved sericin remained constant until a dissolution time of 5 min, following which deterioration was observed. The optimum condition of dissolution of the extracted sericin solid was 5 min at 90 °C. Conclusively, the extracted sericin could be stored in a dry state and dissolved to prepare redissolved sericin aqueous solution with the same MW as extracted sericin, thereby improving the storage stability of the sericin aqueous solution.
ISSN:2073-4360
2073-4360
DOI:10.3390/polym15163405