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Watchful Waiting After Radiological Guided Drainage of Intra-abdominal Abscess in Patients With Crohn’s Disease Might Be Associated With Increased Rates of Stoma Construction

Abstract Background Management of spontaneous intra-abdominal abscess (IAA) in patients with Crohn’s disease (CD) with radiologically guided percutaneous drainage (PD) was debated. Methods This is a secondary analysis from a multicenter, retrospective cohort study of all the patients with CD who und...

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Published in:Crohn's & colitis 360 2023-07, Vol.5 (3), p.otad038-otad038
Main Authors: El-Hussuna, Alaa, Steenholdt, Casper, Merrild Karer, Mette Louise, Nyggard Uldall Nielsen, Natasja, Mujukian, Angela, Fleshner, Phillip R, Iesalnieks, Igors, Horesh, Nir, Kopylov, Uri, Jacoby, Harel, Alqaisi, Hayder Mahmood Waheeb, Colombo, Francesco, Sampietro, Gianluca M, Marino, Marco V, Ellebæk, Mark, Sørensen, Nina, Celentano, Valerio, Ladwa, Nikhil, Warusavitarne, Janindra, Pellino, Gianluca, Zeb, Aurang, Di Candido, Francesca, Hurtado-Pardo, Luis, Frasson, Matteo, Kunovsky, Lumir, Yalcinkaya, Ali, Alonso, Sandra, Pera, Miguel, Rodríguez, Cristina Antón, Bravo, Ana-Minaya, Granero, Alvaro Garcia, Tatar, Ozan Can, Spinelli, Antonino, Qvist, Niels
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Language:English
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Summary:Abstract Background Management of spontaneous intra-abdominal abscess (IAA) in patients with Crohn’s disease (CD) with radiologically guided percutaneous drainage (PD) was debated. Methods This is a secondary analysis from a multicenter, retrospective cohort study of all the patients with CD who underwent PD followed by surgery at 19 international tertiary centers. Results Seventeen patients (4.8%) who did not undergo surgery after PD were compared to those who had PD followed by surgical intervention 335/352 (95.2%). Patients who had PD without surgery were those with longer disease duration, more frequently had previous surgery for CD (laparotomies/laparoscopies), enteric fistula, on steroid treatment before and continue to have it after PD. Patients who had PD without subsequent surgical resection had a higher risk of stoma construction at later stages 8/17 (47.1%) versus 90/326 (27.6%) (P 
ISSN:2631-827X
2631-827X
DOI:10.1093/crocol/otad038