Cardiac Transthyretin Amyloidosis With Coincident Paget’s Disease: A Case Report

Cardiac amyloidosis is a condition that results from the accumulation of amyloid proteins in the extracellular matrix of the myocardium. The diagnosis of this disease was challenging as it lacked distinct clinical symptoms and required a biopsy to confirm amyloid deposition. However, there is increa...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2023-07, Vol.15 (7)
Main Authors: ALQattan, Mohmmad H, Alqadhi, Mukhtar A, AlKhamis, Abdullah A, Alawadh, Ali M, Al Omair, Abdulmajeed M
Format: Article
Language:English
Subjects:
Amyloidosis
Asymptomatic
Cardiac arrhythmia
Cardiology
Carpal tunnel syndrome
Case reports
Electrocardiography
Heart failure
Hypertension
Immunoglobulins
Medical diagnosis
Nuclear Medicine
Patients
Phosphatase
Proteins
Radiology
Scintigraphy
Tomography
Ultrasonic imaging
Urine
Vital signs
Citations: Items that this one cites
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Description
Summary:Cardiac amyloidosis is a condition that results from the accumulation of amyloid proteins in the extracellular matrix of the myocardium. The diagnosis of this disease was challenging as it lacked distinct clinical symptoms and required a biopsy to confirm amyloid deposition. However, there is increasing evidence of non-invasive diagnostic criteria for cardiac amyloidosis, especially for the transthyretin (TTR) type. We report a case of a patient with both cardiac transthyretin amyloidosis (ATTR) and Paget's disease, and we highlight the various radiological features of these two conditions using hybrid imaging techniques. In addition, we discuss the diagnostic imaging characteristics of ATTR cardiac amyloidosis.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.42621