Real‐Time Monitoring of Multitarget Antimicrobial Mechanisms of Peptoids Using Label‐Free Imaging with Optical Diffraction Tomography (Adv. Sci. 24/2023)

Optical Diffraction Tomography Article number 2302483 by Seongsoo Lee, Jiwon Seo, and co‐workers presents the first demonstration of optical diffraction tomography (ODT) being successfully applied to monitor bacterial phenotypical changes in a real‐time and label‐free manner upon treatment of antimi...

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Published in:Advanced science 2023-08, Vol.10 (24), p.n/a
Main Authors: Kim, Minsang, Cheon, Yeongmi, Shin, Dongmin, Choi, Jieun, Nielsen, Josefine Eilsø, Jeong, Myeong Seon, Nam, Ho Yeon, Kim, Sung‐Hak, Lund, Reidar, Jenssen, Håvard, Barron, Annelise E., Lee, Seongsoo, Seo, Jiwon
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Language:English
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Summary:Optical Diffraction Tomography Article number 2302483 by Seongsoo Lee, Jiwon Seo, and co‐workers presents the first demonstration of optical diffraction tomography (ODT) being successfully applied to monitor bacterial phenotypical changes in a real‐time and label‐free manner upon treatment of antimicrobial peptides (AMPs) and peptoids. ODT can be an established imaging technique for investigating mechanisms of action of various antimicrobials.
ISSN:2198-3844
2198-3844
DOI:10.1002/advs.202370159