Prevalence of Osteopathy In Chronic Pancreatitis: A Systematic Review and Meta-Analysis

& Aims: Individuals with chronic pancreatitis are at increased risk for nutritional complications during their clinical course. We appraised the literature to provide updated estimates of the prevalence and predictors of osteoporosis, osteopenia, and osteopathy in chronic pancreatitis using a sy...

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Published in:Clinical and translational gastroenterology 2023-08, Vol.14 (8), p.e00623-e00623
Main Authors: Ramai, Daryl, Facciorusso, Antonio, Maida, Marcello, Capurso, Gabriele, Chandan, Saurabh, Spadaccini, Marco, Rossi, Roberta Elisa, Hassan, Cesare, Repici, Alessandro, Duggan, Sinead, Conwell, Darwin L., Hart, Phil A.
Format: Article
Language:English
Subjects:
Pancreas
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Summary:& Aims: Individuals with chronic pancreatitis are at increased risk for nutritional complications during their clinical course. We appraised the literature to provide updated estimates of the prevalence and predictors of osteoporosis, osteopenia, and osteopathy in chronic pancreatitis using a systematic review and meta-analysis. Search strategies were developed for major databases from inception through October 2021. Outcomes of interest included rates of osteopenia and osteoporosis based on DXA scan as well as risk factors. A random effects model was used for analysis and results were expressed as pooled cumulative rates along with 95% confidence interval (CI). From an initial total of 1704 identified articles, we ultimately selected 17 studies which involved 1,659 subjects (n=1067 men) with chronic pancreatitis. The pooled rate of osteopathy was 58% (95% Confidence Interval (CI): 49% - 67%; P
ISSN:2155-384X
2155-384X
DOI:10.14309/ctg.0000000000000623