Yield & accuracy of Gastric Lavage in non-expectorating adults with Suspected Pulmonary Tuberculosis

• Published in: Pakistan journal of medical sciences 2023-10, Vol.39 (5), p.1468-1472
• Main Authors: Ghafoor, Lubna, Zuberi, Faisal Faiyaz, Khan, Ghulam Muqtada, Ismail, Maria
• Format: Article
• Language: English
• Subjects: Accuracy; Adults; Cavitation; Complaints; Developing countries; Drug resistance; Esophagus; Females; Fever; Gastric lavage; Gender; LDCs; Original; Patients; Pulmonary tuberculosis; Tuberculosis
• ISSN: 1682-024X; 1681-715X
• DOI: 10.12669/pjms.39.5.6972

Objective: To determine the yield of Gastric lavage (GL) in non-expectorating adults with suspected Pulmonary Tuberculosis (PTB) and accuracy of GL-AFB smear with GL-GeneXpert (GXP) by taking AFB culture as gold standard. Methods: Cross-sectional study on suspected PTB patients was done at Ojha Institute of Chest Diseases during period 16th July 2020 till 15th January 2021. Adult patients of either gender suspected to have PTB and not expectorating were included. GL was performed and sent for AFB smear, GXP and AFB culture. Odds ratio, sensitivity and specificity were calculated. Results: After informed written consent, 206 patients, mean age was 38.17 ±17.30 years were inducted, including 89 (43.2%) males and 117 (56.8%) females. Gene Xpert, AFB smear & AFB culture were positive in 83(40%), 50 (24%) & 72 (35%) respectively in GL samples. Odds of PTB were 3.95 times higher among patients with ≤1 month of duration of symptoms (aOR 3.95, 95% CI 1.82-8.57, p-value 0.001), 6.24 times higher among patients with weight loss (aOR 6.24, 95% CI 3.03-12.84, p-value