Patient-reported pain associated with grid-based transperineal magnetic resonance imaging (MRI)/ultrasound (US) software fusion biopsy of the prostate under local anesthesia: a multicenter experience

• Published in: Translational andrology and urology 2023-08, Vol.12 (8), p.1250-1258
• Main Authors: Szempliński, Stanisław, Kamecki, Hubert, Mokrzyś, Mateusz, Zawadzki, Marek, Zagożdżon, Bartłomiej, Dębowska, Małgorzata, Sosnowski, Roman, Poletajew, Sławomir, Kryst, Piotr, Nyk, Łukasz
• Format: Article
• Language: English
• Subjects: Original
• ISSN: 2223-4683; 2223-4691; 2223-4691
• DOI: 10.21037/tau-23-139

BackgroundBiopsy by transperineal (TP) approach is recommended standard for prostate cancer (PC) diagnosis. To avoid pain, patients undergoing TP biopsy may be offered sedation or general anesthesia. Our aim was to investigate the degree of patient-reported pain for magnetic resonance imaging (MRI)/ultrasound (US) fusion biopsy of the prostate being performed under local anesthesia (LA) and to study for possible factors associated with increased risk of significant pain (SP) in this setting. MethodsIn this retrospective observational study, we reviewed data of consecutive patients without a prior diagnosis of PC who underwent MRI/US software fusion biopsy of the prostate under LA with lidocaine at two centers between May 2020 and April 2022, and who reported their periprocedural pain on a Wong-Baker FACES Pain Rating Scale (0-10). We defined SP as reported pain score of 6-10. Patient and procedure characteristics together with SP were studied for interdependencies. ResultsA total of 299 patients were included. Median pain score was 2 (interquartile range: 2-4), with SP having been reported by 55 (18.4%) patients. Among patient characteristics, only age demonstrated association with SP [odds ratio (OR), per 10 years =0.53, 95% confidence interval (CI): 0.35-0.80, P=0.003] and patients aged 62 or above were significantly less likely to report SP (OR =0.33, 95% CI: 0.18-0.60, P