Proteolysis and therapeutic potential of bioactive peptides derived from Cheddar cheese

Cheddar cheese-derived bioactive peptides are considered a potential component of functional foods. A positive impact of bioactive peptides on diet-related chronic, non-communicable diseases, like obesity, cardiovascular diseases, and diabetes, has been observed. Bioactive peptides possess multifunc...

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Bibliographic Details
Published in:Food science & nutrition 2023-09, Vol.11 (9), p.4948-4963
Main Authors: Shafique, Bakhtawar, Murtaza, Mian Anjum, Hafiz, Iram, Ameer, Kashif, Basharat, Shahnai, Mohamed Ahmed, Isam A
Format: Article
Language:English
Subjects:
Amino acids
Antibiotics
Antimicrobial agents
Bacteria
Biocompatibility
Biological activity
Cardiovascular disease
Cardiovascular diseases
Cheddar cheese
Cheese
Chronic illnesses
Dairy industry
Dairy products
Diabetes mellitus
Drug resistance
Food safety
Functional foods & nutraceuticals
Gram-positive bacteria
Health promotion
Hypertension
Immunomodulation
Lactose
Lactose intolerance
Milk
Osteoporosis
Peptides
Probiotics
Product development
Proteins
Proteolysis
Review
Reviews
Toxicity
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Summary:Cheddar cheese-derived bioactive peptides are considered a potential component of functional foods. A positive impact of bioactive peptides on diet-related chronic, non-communicable diseases, like obesity, cardiovascular diseases, and diabetes, has been observed. Bioactive peptides possess multifunctional therapeutic potentials, including antimicrobial, immunomodulatory, antioxidant, enzyme inhibitory effects, anti-thrombotic, and phyto-pathological activities against various toxic compounds. Peptides can regulate human immune, gastrointestinal, hormonal, and neurological responses, which play an integral role in the deterrence and treatment of certain diseases like cancer, osteoporosis, hypertension, and other health disorders, as described in the present review. This review summarizes the categories of the Cheddar cheese-derived bioactive peptides, their general characteristics, physiological functions, and possible applications in healthcare.
ISSN:2048-7177
2048-7177
DOI:10.1002/fsn3.3501