Physical therapy in diabetic foot ulcer: Research progress and clinical application

Diabetes foot ulcer (DFU) is one of the most intractable complications of diabetes and is related to a number of risk factors. DFU therapy is difficult and involves long-term interdisciplinary collaboration, causing patients physical and emotional pain and increasing medical costs. With a rising num...

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Bibliographic Details
Published in:International wound journal 2023-10, Vol.20 (8), p.3417-3434
Main Authors: Huang, Hao, Xin, Rujuan, Li, Xiaolong, Zhang, Xinyue, Chen, Zhongjian, Zhu, Quangang, Tai, Zongguang, Bao, Leilei
Format: Article
Language:English
Subjects:
Bacteria
Chronic illnesses
Diabetes
Enzymes
Exercise
Fibroblasts
Foot diseases
Free radicals
Glucose
Growth factors
Hyperglycemia
Hypoxia
Immune system
Inflammation
Insulin
Ischemia
Leg ulcers
Medical prognosis
Metabolism
Nutrition
Oxidative stress
Patients
Peripheral neuropathy
Review
Skin
Wound healing
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Summary:Diabetes foot ulcer (DFU) is one of the most intractable complications of diabetes and is related to a number of risk factors. DFU therapy is difficult and involves long-term interdisciplinary collaboration, causing patients physical and emotional pain and increasing medical costs. With a rising number of diabetes patients, it is vital to figure out the causes and treatment techniques of DFU in a precise and complete manner, which will assist alleviate patients' suffering and decrease excessive medical expenditure. Here, we summarised the characteristics and progress of the physical therapy methods for the DFU, emphasised the important role of appropriate exercise and nutritional supplementation in the treatment of DFU, and discussed the application prospects of non-traditional physical therapy such as electrical stimulation (ES), and photobiomodulation therapy (PBMT) in the treatment of DFU based on clinical experimental records in ClinicalTrials.gov.
ISSN:1742-4801
1742-481X
1742-481X
DOI:10.1111/iwj.14196