Loading…

Management of open fractures: A narrative review

Open fractures are an emergency where the principal aim of the treatment is to maximise the restoration of limb function while preventing the dreaded consequences of infection and non-union. The decision-making process for open injuries is influenced by a variety of criteria, such as patient age, in...

Full description

Saved in:
Bibliographic Details
Published in:Journal of clinical orthopaedics and trauma 2023-09, Vol.44, p.102246, Article 102246
Main Authors: Jayaramaraju, Dheenadhayalan, Vasudeva, Nagashree, Devendra, Agraharam, Sundaram, Velmurugesan Purnaganapathi, Rajasekaran, Shanmuganathan
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c3716-1c4de97c7938b92436d4ae505ab6451654a975b251f17daa7f161725df4d4dda3
cites cdi_FETCH-LOGICAL-c3716-1c4de97c7938b92436d4ae505ab6451654a975b251f17daa7f161725df4d4dda3
container_end_page
container_issue
container_start_page 102246
container_title Journal of clinical orthopaedics and trauma
container_volume 44
creator Jayaramaraju, Dheenadhayalan
Vasudeva, Nagashree
Devendra, Agraharam
Sundaram, Velmurugesan Purnaganapathi
Rajasekaran, Shanmuganathan
description Open fractures are an emergency where the principal aim of the treatment is to maximise the restoration of limb function while preventing the dreaded consequences of infection and non-union. The decision-making process for open injuries is influenced by a variety of criteria, such as patient age, injury features, systemic response, activity level, comorbidities, and functional requirements. A collaborative orthoplastic approach to treating these injuries is essential for minimizing complications and need to be considered as a single specialty in early and long-term management. It has been shown that early prophylactic systemic antibiotics, wound irrigation, aggressive debridement of contaminated and devitalized tissue, and appropriate fracture fixation decreases the complications in all grades of open fractures. The advantages of Gram-negative antibiotics, the use of local antibiotics, intraoperative wound cultures, the "fix and flap" approach, and Negative Pressure Wound Therapy are few of the treatment options that are still controversial. The aim of this review is to provide a comprehensive review and practice guidelines regarding the management of open fractures.
doi_str_mv 10.1016/j.jcot.2023.102246
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10502353</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0976566223001546</els_id><sourcerecordid>2866110629</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3716-1c4de97c7938b92436d4ae505ab6451654a975b251f17daa7f161725df4d4dda3</originalsourceid><addsrcrecordid>eNp9kE1LAzEQhoMoWqp_wIPs0cvWTD67IoiIX6B40XNIk1lNaTc12Vb896ZURS_OZWDmnXdeHkIOgY6AgjqZjqYu9iNGGS8DxoTaIgPGgNdcCLlNBrTRqpZKsT1ykPOUlpIKGhjvkj2uNaNi3AwIfbCdfcE5dn0V2yousKvaZF2_TJhPq4uqsynZPqywSrgK-L5Pdlo7y3jw1Yfk-frq6fK2vn-8ubu8uK8d16BqcMJjo51u-HjSMMGVFxYllXaihAQlhW20nDAJLWhvrW5BgWbSt8IL7y0fkvON72I5maN3JWCyM7NIYW7Th4k2mL-bLryal7gyQGVhInlxOP5ySPFtibk385Adzma2w7jMho2VAqCKNUXKNlKXYs4J258_QM0at5maNW6zxm02uMvR0e-EPyffcIvgbCPAwqmwSya7gJ1DHxK63vgY_vP_BG1wj_I</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2866110629</pqid></control><display><type>article</type><title>Management of open fractures: A narrative review</title><source>ScienceDirect Freedom Collection 2022-2024</source><source>PubMed Central</source><creator>Jayaramaraju, Dheenadhayalan ; Vasudeva, Nagashree ; Devendra, Agraharam ; Sundaram, Velmurugesan Purnaganapathi ; Rajasekaran, Shanmuganathan</creator><creatorcontrib>Jayaramaraju, Dheenadhayalan ; Vasudeva, Nagashree ; Devendra, Agraharam ; Sundaram, Velmurugesan Purnaganapathi ; Rajasekaran, Shanmuganathan</creatorcontrib><description>Open fractures are an emergency where the principal aim of the treatment is to maximise the restoration of limb function while preventing the dreaded consequences of infection and non-union. The decision-making process for open injuries is influenced by a variety of criteria, such as patient age, injury features, systemic response, activity level, comorbidities, and functional requirements. A collaborative orthoplastic approach to treating these injuries is essential for minimizing complications and need to be considered as a single specialty in early and long-term management. It has been shown that early prophylactic systemic antibiotics, wound irrigation, aggressive debridement of contaminated and devitalized tissue, and appropriate fracture fixation decreases the complications in all grades of open fractures. The advantages of Gram-negative antibiotics, the use of local antibiotics, intraoperative wound cultures, the "fix and flap" approach, and Negative Pressure Wound Therapy are few of the treatment options that are still controversial. The aim of this review is to provide a comprehensive review and practice guidelines regarding the management of open fractures.</description><identifier>ISSN: 0976-5662</identifier><identifier>EISSN: 2213-3445</identifier><identifier>DOI: 10.1016/j.jcot.2023.102246</identifier><identifier>PMID: 37720489</identifier><language>eng</language><publisher>India: Elsevier B.V</publisher><subject>Debridement ; Ganga hospital open injury severity score ; General Orthopaedics and Others ; Open fractures ; Orthoplastic approach ; Wound irrigation</subject><ispartof>Journal of clinical orthopaedics and trauma, 2023-09, Vol.44, p.102246, Article 102246</ispartof><rights>2023</rights><rights>2023.</rights><rights>2023. 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3716-1c4de97c7938b92436d4ae505ab6451654a975b251f17daa7f161725df4d4dda3</citedby><cites>FETCH-LOGICAL-c3716-1c4de97c7938b92436d4ae505ab6451654a975b251f17daa7f161725df4d4dda3</cites><orcidid>0000-0001-6043-006X ; 0000-0001-5007-3644 ; 0000-0002-8461-0767 ; 0000-0002-5713-2616 ; 0000-0002-1295-136X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502353/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502353/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37720489$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jayaramaraju, Dheenadhayalan</creatorcontrib><creatorcontrib>Vasudeva, Nagashree</creatorcontrib><creatorcontrib>Devendra, Agraharam</creatorcontrib><creatorcontrib>Sundaram, Velmurugesan Purnaganapathi</creatorcontrib><creatorcontrib>Rajasekaran, Shanmuganathan</creatorcontrib><title>Management of open fractures: A narrative review</title><title>Journal of clinical orthopaedics and trauma</title><addtitle>J Clin Orthop Trauma</addtitle><description>Open fractures are an emergency where the principal aim of the treatment is to maximise the restoration of limb function while preventing the dreaded consequences of infection and non-union. The decision-making process for open injuries is influenced by a variety of criteria, such as patient age, injury features, systemic response, activity level, comorbidities, and functional requirements. A collaborative orthoplastic approach to treating these injuries is essential for minimizing complications and need to be considered as a single specialty in early and long-term management. It has been shown that early prophylactic systemic antibiotics, wound irrigation, aggressive debridement of contaminated and devitalized tissue, and appropriate fracture fixation decreases the complications in all grades of open fractures. The advantages of Gram-negative antibiotics, the use of local antibiotics, intraoperative wound cultures, the "fix and flap" approach, and Negative Pressure Wound Therapy are few of the treatment options that are still controversial. The aim of this review is to provide a comprehensive review and practice guidelines regarding the management of open fractures.</description><subject>Debridement</subject><subject>Ganga hospital open injury severity score</subject><subject>General Orthopaedics and Others</subject><subject>Open fractures</subject><subject>Orthoplastic approach</subject><subject>Wound irrigation</subject><issn>0976-5662</issn><issn>2213-3445</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp9kE1LAzEQhoMoWqp_wIPs0cvWTD67IoiIX6B40XNIk1lNaTc12Vb896ZURS_OZWDmnXdeHkIOgY6AgjqZjqYu9iNGGS8DxoTaIgPGgNdcCLlNBrTRqpZKsT1ykPOUlpIKGhjvkj2uNaNi3AwIfbCdfcE5dn0V2yousKvaZF2_TJhPq4uqsynZPqywSrgK-L5Pdlo7y3jw1Yfk-frq6fK2vn-8ubu8uK8d16BqcMJjo51u-HjSMMGVFxYllXaihAQlhW20nDAJLWhvrW5BgWbSt8IL7y0fkvON72I5maN3JWCyM7NIYW7Th4k2mL-bLryal7gyQGVhInlxOP5ySPFtibk385Adzma2w7jMho2VAqCKNUXKNlKXYs4J258_QM0at5maNW6zxm02uMvR0e-EPyffcIvgbCPAwqmwSya7gJ1DHxK63vgY_vP_BG1wj_I</recordid><startdate>202309</startdate><enddate>202309</enddate><creator>Jayaramaraju, Dheenadhayalan</creator><creator>Vasudeva, Nagashree</creator><creator>Devendra, Agraharam</creator><creator>Sundaram, Velmurugesan Purnaganapathi</creator><creator>Rajasekaran, Shanmuganathan</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-6043-006X</orcidid><orcidid>https://orcid.org/0000-0001-5007-3644</orcidid><orcidid>https://orcid.org/0000-0002-8461-0767</orcidid><orcidid>https://orcid.org/0000-0002-5713-2616</orcidid><orcidid>https://orcid.org/0000-0002-1295-136X</orcidid></search><sort><creationdate>202309</creationdate><title>Management of open fractures: A narrative review</title><author>Jayaramaraju, Dheenadhayalan ; Vasudeva, Nagashree ; Devendra, Agraharam ; Sundaram, Velmurugesan Purnaganapathi ; Rajasekaran, Shanmuganathan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3716-1c4de97c7938b92436d4ae505ab6451654a975b251f17daa7f161725df4d4dda3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Debridement</topic><topic>Ganga hospital open injury severity score</topic><topic>General Orthopaedics and Others</topic><topic>Open fractures</topic><topic>Orthoplastic approach</topic><topic>Wound irrigation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jayaramaraju, Dheenadhayalan</creatorcontrib><creatorcontrib>Vasudeva, Nagashree</creatorcontrib><creatorcontrib>Devendra, Agraharam</creatorcontrib><creatorcontrib>Sundaram, Velmurugesan Purnaganapathi</creatorcontrib><creatorcontrib>Rajasekaran, Shanmuganathan</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical orthopaedics and trauma</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jayaramaraju, Dheenadhayalan</au><au>Vasudeva, Nagashree</au><au>Devendra, Agraharam</au><au>Sundaram, Velmurugesan Purnaganapathi</au><au>Rajasekaran, Shanmuganathan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Management of open fractures: A narrative review</atitle><jtitle>Journal of clinical orthopaedics and trauma</jtitle><addtitle>J Clin Orthop Trauma</addtitle><date>2023-09</date><risdate>2023</risdate><volume>44</volume><spage>102246</spage><pages>102246-</pages><artnum>102246</artnum><issn>0976-5662</issn><eissn>2213-3445</eissn><abstract>Open fractures are an emergency where the principal aim of the treatment is to maximise the restoration of limb function while preventing the dreaded consequences of infection and non-union. The decision-making process for open injuries is influenced by a variety of criteria, such as patient age, injury features, systemic response, activity level, comorbidities, and functional requirements. A collaborative orthoplastic approach to treating these injuries is essential for minimizing complications and need to be considered as a single specialty in early and long-term management. It has been shown that early prophylactic systemic antibiotics, wound irrigation, aggressive debridement of contaminated and devitalized tissue, and appropriate fracture fixation decreases the complications in all grades of open fractures. The advantages of Gram-negative antibiotics, the use of local antibiotics, intraoperative wound cultures, the "fix and flap" approach, and Negative Pressure Wound Therapy are few of the treatment options that are still controversial. The aim of this review is to provide a comprehensive review and practice guidelines regarding the management of open fractures.</abstract><cop>India</cop><pub>Elsevier B.V</pub><pmid>37720489</pmid><doi>10.1016/j.jcot.2023.102246</doi><orcidid>https://orcid.org/0000-0001-6043-006X</orcidid><orcidid>https://orcid.org/0000-0001-5007-3644</orcidid><orcidid>https://orcid.org/0000-0002-8461-0767</orcidid><orcidid>https://orcid.org/0000-0002-5713-2616</orcidid><orcidid>https://orcid.org/0000-0002-1295-136X</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0976-5662
ispartof Journal of clinical orthopaedics and trauma, 2023-09, Vol.44, p.102246, Article 102246
issn 0976-5662
2213-3445
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10502353
source ScienceDirect Freedom Collection 2022-2024; PubMed Central
subjects Debridement
Ganga hospital open injury severity score
General Orthopaedics and Others
Open fractures
Orthoplastic approach
Wound irrigation
title Management of open fractures: A narrative review
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T05%3A15%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Management%20of%20open%20fractures:%20A%20narrative%20review&rft.jtitle=Journal%20of%20clinical%20orthopaedics%20and%20trauma&rft.au=Jayaramaraju,%20Dheenadhayalan&rft.date=2023-09&rft.volume=44&rft.spage=102246&rft.pages=102246-&rft.artnum=102246&rft.issn=0976-5662&rft.eissn=2213-3445&rft_id=info:doi/10.1016/j.jcot.2023.102246&rft_dat=%3Cproquest_pubme%3E2866110629%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3716-1c4de97c7938b92436d4ae505ab6451654a975b251f17daa7f161725df4d4dda3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2866110629&rft_id=info:pmid/37720489&rfr_iscdi=true