Molecular docking analysis of protein filamin-A with thioazo compounds

It is of interest to document the molecular docking analysis of protein Filamin-A with thioazo compounds. The compounds 1, 3, 5, and 6 showed best molecular docking interaction as compared to the drug doxorubicin. Among the selected ligands (1-6), compound 3 shows better interaction score than doxor...

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Bibliographic Details
Published in:Bioinformation 2023-01, Vol.19 (1), p.99-104
Main Author: Satish, Sudarshan
Format: Article
Language:English
Online Access:Get full text
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Summary:It is of interest to document the molecular docking analysis of protein Filamin-A with thioazo compounds. The compounds 1, 3, 5, and 6 showed best molecular docking interaction as compared to the drug doxorubicin. Among the selected ligands (1-6), compound 3 shows better interaction score than doxorubicin and follows Lipinski's rule of five. Hence, it could be considered as a potential lead molecule for inhibiting protein filamin A in the treatment of oral cancer.
ISSN:0973-8894
0973-2063
0973-2063
DOI:10.6026/97320630019099