The Moderating Role of Social Support and HIV Stigma on the Association Between Depression and ART Adherence Among Young Thai Men Who Have Sex with Men

In Thailand, antiretroviral therapy (ART) programs still have difficulties reaching and promoting adherence among a key population - young men who have sex with men (YMSM) living with HIV. As such, we sought to examine potential psychosocial barriers that may contribute to suboptimal levels of ART a...

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Bibliographic Details
Published in:AIDS and behavior 2023-09, Vol.27 (9), p.2959-2968
Main Authors: Mireles, Linda, Horvath, Keith J., Guadamuz, Thomas E., Waratworawan, Worawalan, Kongjareon, Yamol, Meyers-Pantele, Stephanie A.
Format: Article
Language:English
Subjects:
Antiretroviral agents
Antiretroviral drugs
Antiretroviral therapy
Depression - psychology
Gays & lesbians
Health Psychology
HIV
HIV Infections - drug therapy
HIV Infections - epidemiology
HIV Infections - psychology
Homosexuality, Male - psychology
Human immunodeficiency virus
Humans
Infectious Diseases
Male
Medication Adherence - psychology
Medicine
Medicine & Public Health
Men who have sex with men
Mens health
Mental depression
Original Paper
Patient compliance
Public Health
Regression analysis
Regression models
Sexual and Gender Minorities
Sexually transmitted diseases
Social interactions
Social Stigma
Social Support
Southeast Asian People
STD
Stigma
Thailand - epidemiology
Young men
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Summary:In Thailand, antiretroviral therapy (ART) programs still have difficulties reaching and promoting adherence among a key population - young men who have sex with men (YMSM) living with HIV. As such, we sought to examine potential psychosocial barriers that may contribute to suboptimal levels of ART adherence for this population. Data were drawn from a study of 214 YMSM living with HIV from Bangkok, Thailand. Linear regression models tested the association between depression and ART adherence, and whether social support and HIV-related stigma moderated that relationship. Multivariable models demonstrated social support was significantly associated with higher levels of ART adherence, and that there was a three-way interaction between depression, social support, and HIV-related stigma on ART adherence. These results further our understanding of the role of depression, stigma, and social support in ART adherence among Thai YMSM living with HIV, and that additional supports for YMSM with depression and HIV-related stigma are needed.
ISSN:1090-7165
1573-3254
1573-3254
DOI:10.1007/s10461-023-04018-y