Real-Time Ultrasonography and the Evaluation of Static Images Yield Different Results in the Assessment of EU-TIRADS Categories

• Published in: Journal of clinical medicine 2023-09, Vol.12 (18), p.5809
• Main Authors: Słowińska-Klencka, Dorota, Popowicz, Bożena, Klencki, Mariusz
• Format: Article
• Language: English
• Subjects: Analysis; Biopsy, Needle; Care and treatment; Classification; Clinical medicine; Diagnosis; Real time; Reproducibility; Thyroid cancer; Thyroid diseases; Thyroid gland; Ultrasonic imaging; Ultrasound imaging
• ISSN: 2077-0383; 2077-0383
• DOI: 10.3390/jcm12185809

The studies on the effectiveness of various TIRADS in the diagnostics of thyroid nodules differ in the method of ultrasound image assessment: real time (rtUS) vs. static ultrasonography (stUS). The aim of the study was to evaluate the impact of those two methods on the categorization of nodules in EU-TIRADS. Three experienced raters assessed 842 nodules in routine rtUS and reassessed with the use of sUS. Reproducibility of the assessment of malignancy risk features and categorization of nodules with EU-TIRADS was estimated with Krippendorff’s alpha coefficient (Kα). The reproducibility of EU-TIRADS categories on sUS in relation to rtUS was in range 70.9–76.5% for all raters (Kα: 0.60–0.68) with the highest reproducibility for category 3 (80.0–86.5%) and the lowest for category 5 (48.7–77.8%). There was a total disagreement of the identification of microcalcifications on sUS in relation to rtUS, a strongly variable reproducibility of marked hypoechogenicity (12.5–84.6%, Kα: 0.14–0.48) and a tendency toward more frequent identification of the non-oval shape on sUS. The percentage of agreement for each pair of raters in assigning the EU-TIRADS category on sUS was in the range 71.6–72.3% (Kα: 0.60–0.62). The method of sonographic image evaluation influences the nodule’s feature assessment and, eventually, the categorization within EU-TIRADS.