PROMIS: Physical, Mental and Social Health Outcomes Improve From Before to Early After LVAD Implant: Findings From the Mechanical Circulatory Support: Measures of Adjustment and Quality of Life (MCS A-QOL) Study

• Published in: Journal of cardiac failure 2023-10, Vol.29 (10), p.1398-1411
• Main Authors: HAHN, ELIZABETH A., ALLEN, LARRY A., LEE, CHRISTOPHER S., DENFELD, QUIN E., STEHLIK, JOSEF, CELLA, DAVID, LINDENFELD, JOANN, TEUTEBERG, JEFFREY J., MCILVENNAN, COLLEEN K., KIERNAN, MICHAEL S., BEISER, DAVID G., WALSH, MARY N., ADLER, ERIC D., RUO, BERNICE, KIRKLIN, JAMES K., KLEIN, LIVIU, BEDJETI, KATY, CUMMINGS, PETER D., BURNS, JAMES L., VELA, ALYSSA M., GRADY, KATHLEEN L.
• Format: Article
• Language: English
• Subjects: Adaptation, Psychological; Adult; Aged; Female; Follow-Up Studies; Health Status; Heart failure; Heart Failure - psychology; Heart Failure - surgery; Heart Failure - therapy; Heart-Assist Devices - psychology; Humans; left ventricular assist device; longitudinal study; Male; Mental Health; Middle Aged; Patient Reported Outcome Measures; patient-reported outcomes; Quality of Life - psychology; Surveys and Questionnaires; Time Factors; Treatment Outcome
• ISSN: 1071-9164; 1532-8414; 1532-8414
• DOI: 10.1016/j.cardfail.2023.03.013

[Display omitted] •Patient-reported outcomes (PROs) are especially important for people who receive left ventricular assist devices (LVADs), given their lifestyle changes, LVAD-focused self-care needs and the potential for device-related adverse events.•Patient-Reported Outcomes Measurement Information System (PROMIS) physical, mental and social health measures are advantageous for use in multiple chronic illnesses because they allow comparability of experiences across diseases/conditions.•Tracking changes in PRO outcomes across time in individual patients could provide patients and clinicians with the opportunity to identify positive and negative changes and ways to address them. Study participants (n = 272) completed 12 Patient-Reported Outcomes Measurement Information System (PROMIS) physical, mental and social health measures (questionnaires) prior to implantation of a left ventricular assist device (LVAD) and again at 3 and 6 months postimplant. All but 1 PROMIS measure demonstrated significant improvement from pre-implant to 3 months; there was little change between 3 and 6 months. Because PROMIS measures were developed in the general population, patients with an LVAD, their caregivers and their clinicians can interpret the meaning of PROMIS scores in relation to the general population, helping them to monitor a return to normalcy in everyday life.