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The Human Mpox Global Outbreak: Available Control Tools and the Opportunity to Break a Cycle of Neglect in Endemic Countries

The 2022 global outbreak of human Mpox (formerly monkeypox) virus (MPXV) infection outside of the usual endemic zones in Africa challenged our understanding of the virus's natural history, transmission dynamics, and risk factors. This outbreak has highlighted the need for diagnostics, vaccines,...

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Published in:	The American journal of tropical medicine and hygiene 2023-10, Vol.109 (4), p.719-724
Main Authors:	Nachega, Jean B, Mbala-Kingebeni, Placide, Rosenthal, Philip J, Rimoin, Anne W, Hoff, Nicole A, Liesenborghs, Laurens, Vanlerberghe, Veerle, Andrei, Graciela, Rawat, Angeli, Wilson, Lindsay A, Forrest, Jamie, Mills, Edward J, Hermans, Michel P, Mulangu, Sabue, Ntoumi, Francine, Zumla, Alimuddin, Muyembe-Tamfum, Jean-Jacques
Format:	Article
Language:	English
Subjects:	Animals Disease control Disease Outbreaks - prevention & control Disease transmission Endemic Diseases - prevention & control Epidemics Global Health Health risks Humans Monkeypox virus Mpox Mpox (monkeypox) - epidemiology Mpox (monkeypox) - prevention & control Pathogens Review Zoonoses - epidemiology Zoonoses - prevention & control
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creator	Nachega, Jean B Mbala-Kingebeni, Placide Rosenthal, Philip J Rimoin, Anne W Hoff, Nicole A Liesenborghs, Laurens Vanlerberghe, Veerle Andrei, Graciela Rawat, Angeli Wilson, Lindsay A Forrest, Jamie Mills, Edward J Hermans, Michel P Mulangu, Sabue Ntoumi, Francine Zumla, Alimuddin Muyembe-Tamfum, Jean-Jacques
description	The 2022 global outbreak of human Mpox (formerly monkeypox) virus (MPXV) infection outside of the usual endemic zones in Africa challenged our understanding of the virus's natural history, transmission dynamics, and risk factors. This outbreak has highlighted the need for diagnostics, vaccines, therapeutics, and implementation research, all of which require more substantial investments in equitable collaborative partnerships. Global multidisciplinary networks need to tackle MPXV and other neglected emerging and reemerging zoonotic pathogens to address them locally and prevent or quickly control their worldwide spread. Political endorsement from individual countries and financial commitments to maintain control efforts will be essential for long-term sustainability.
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subjects	Animals Disease control Disease Outbreaks - prevention & control Disease transmission Endemic Diseases - prevention & control Epidemics Global Health Health risks Humans Monkeypox virus Mpox Mpox (monkeypox) - epidemiology Mpox (monkeypox) - prevention & control Pathogens Review Zoonoses - epidemiology Zoonoses - prevention & control
title	The Human Mpox Global Outbreak: Available Control Tools and the Opportunity to Break a Cycle of Neglect in Endemic Countries
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