Molecular docking analysis of proflavin with the Wnt pathway targets for OSCC

Wnt signaling pathway plays a critical role in tumor progression and metastasis of various cancer types. Therefore, it is of interest to document the molecular docking analysis of proflavin with the Wnt pathway targets (GSK3β, β-catenin, and VIM) for oral squamous cell carcinoma (OSCC). These result...

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Bibliographic Details
Published in:Bioinformation 2023-04, Vol.19 (4), p.464-466
Main Author: Jayaraman, Selvaraj
Format: Article
Language:English
Online Access:Get full text
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Summary:Wnt signaling pathway plays a critical role in tumor progression and metastasis of various cancer types. Therefore, it is of interest to document the molecular docking analysis of proflavin with the Wnt pathway targets (GSK3β, β-catenin, and VIM) for oral squamous cell carcinoma (OSCC). These results suggest that targeting the wnt signaling downstream targets with proflavine might leads to the better outcome for therapeutic outcome for the inhibition of invasion and metastasis in oral squamous cell carcinoma.
ISSN:0973-8894
0973-2063
0973-2063
DOI:10.6026/97320630019464