Molecular docking and dynamics simulation of main protease of SARS-CoV-2 with naproxen derivative

Naproxen is a well-known anti-inflammatory drug that is frequently used to relieve inflammation, stiffness, and swelling. Naproxen has previously demonstrated antiviral activity, particularly against the influenza-A virus. There have been previous studies regarding naproxen effect on SARS-CoV-2 infe...

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Bibliographic Details
Published in:Bioinformation 2023-04, Vol.19 (4), p.358-361
Main Authors: K Hussein, Rageh, Marashdeh, Mohammad, M El-Khayatt, Ahmed
Format: Article
Language:English
Subjects:
Anti-inflammatory agents
Antiviral activity
Inflammation
Molecular docking
Naproxen
Protease
Severe acute respiratory syndrome coronavirus 2
Simulation
Stiffness
Viral diseases
Viruses
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Summary:Naproxen is a well-known anti-inflammatory drug that is frequently used to relieve inflammation, stiffness, and swelling. Naproxen has previously demonstrated antiviral activity, particularly against the influenza-A virus. There have been previous studies regarding naproxen effect on SARS-CoV-2 infection. Therefore, it is of interest to document the molecular docking and dynamics simulation data of main protease of SARS-CoV-2 with naproxen derivative for further consideration.
ISSN:0973-2063
0973-8894
0973-2063
DOI:10.6026/97320630019358