Comparison of post contrast fluid attenuated inversion recovery, 3D T1-SPACE, and T1W MRI sequences with fat suppression in the diagnosis of infectious meningitis

Objective To assess the usefulness of post contrast Fluid attenuated inversion recovery (FLAIR), 3D T1-SPACE, and T1W magnetic resonance imaging (MRI) sequences with fat suppression in diagnosis of infectious meningitis. Methods 75 patients with clinical suspicion of meningitis were evaluated with p...

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Published in:The neuroradiology journal 2023-10, Vol.36 (5), p.572-580
Main Authors: Mishra, Satyakam, Naik, Suprava, Bhoi, Sanjeev Kumar, Kumar, Mukesh, Deep (Bag), Nerbadyswari, Dey, Anupam, Mohakud, Sudipta, Mahapatro, Samarendra
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Language:English
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Summary:Objective To assess the usefulness of post contrast Fluid attenuated inversion recovery (FLAIR), 3D T1-SPACE, and T1W magnetic resonance imaging (MRI) sequences with fat suppression in diagnosis of infectious meningitis. Methods 75 patients with clinical suspicion of meningitis were evaluated with post contrast FLAIR (PC-FLAIR), post contrast T1-SPACE (PC-T1-SPACE), and post contrast T1WI (PC-T1WI). Sensitivity, specificity, positive predictive value, and negative predictive value of individual sequences were assessed. Results The sensitivity of PC-FLAIR (88.4%) was greater than PC-T1-SPACE (85.5%) and PC-T1WI (82.6%), considering cerebrospinal fluid (CSF) analysis as gold standard (p < 0.05). Kappa inter-rater agreement between two radiologists was 0.921 for PC-T1-SPACE, 0.921 for PC-T1WI, and 1.0 for PC-FLAIR with a p value
ISSN:1971-4009
2385-1996
DOI:10.1177/19714009231163563