Racial disparities in women with ST elevation myocardial infarction: A National Inpatient Sample review of baseline characteristics, co-morbidities, and outcomes in women with STEMI

A third of the patients admitted with Acute coronary syndrome (ACS) have ST-elevation myocardial infarction (STEMI). Previous studies showed that females with STEMI have higher mortality than men. There exist significant disparities in outcomes among women of different races presenting with STEMI. N...

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Published in:Clinical cardiology (Mahwah, N.J.) N.J.), 2023-10, Vol.46 (10), p.1285-1295
Main Authors: Senthil Kumaran, Sriviji, Del Cid Fratti, Juan, Desai, Anjali, Garg, Rimmy, Requeña-Armas, Carlos, Barzallo, Pablo, Henien, Mena, Ahmad, Mansoor, Mungee, Sudhir, Mukhopadhyay, Ekanka, Kizhakekuttu, Tinoy
Format: Article
Language:English
Subjects:
African Americans
Cardiac arrhythmia
Cardiovascular disease
Carotid arteries
Chronic obstructive pulmonary disease
Clinical Trial Result
Comorbidity
Females
Health services utilization
Heart attacks
Hispanic Americans
Hospitalization
Hospitals
Length of stay
Medicaid
Medicare
Minority & ethnic groups
Mortality
Patients
Population
Pulmonary arteries
Race
Regression analysis
Vein & artery diseases
Ventilators
White people
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container_title Clinical cardiology (Mahwah, N.J.)
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creator Senthil Kumaran, Sriviji
Del Cid Fratti, Juan
Desai, Anjali
Garg, Rimmy
Requeña-Armas, Carlos
Barzallo, Pablo
Henien, Mena
Ahmad, Mansoor
Mungee, Sudhir
Mukhopadhyay, Ekanka
Kizhakekuttu, Tinoy
description A third of the patients admitted with Acute coronary syndrome (ACS) have ST-elevation myocardial infarction (STEMI). Previous studies showed that females with STEMI have higher mortality than men. There exist significant disparities in outcomes among women of different races presenting with STEMI. National inpatient sample (NIS) data was obtained from January 2016 to December 2018 for the hospitalization of female patients with STEMI. We compared outcomes, using an extensive multivariate regression analysis amongst women from different races. Our primary outcome was in-hospital mortality. Secondary outcomes were revascularization use, procedure complications, and healthcare utilization. Of 202 223 female patients with STEMI; 11.3% were African American, 7.4% Hispanic, 2.4% Asian, and 4.3% another race. In-hospital mortality was higher in non-Caucasian groups. African American (adjusted odds ratio [aOR] 1.2; 95% confidence interval [CI]: 1.07-1.30; p 
doi_str_mv 10.1002/clc.24068
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Previous studies showed that females with STEMI have higher mortality than men. There exist significant disparities in outcomes among women of different races presenting with STEMI. National inpatient sample (NIS) data was obtained from January 2016 to December 2018 for the hospitalization of female patients with STEMI. We compared outcomes, using an extensive multivariate regression analysis amongst women from different races. Our primary outcome was in-hospital mortality. Secondary outcomes were revascularization use, procedure complications, and healthcare utilization. Of 202 223 female patients with STEMI; 11.3% were African American, 7.4% Hispanic, 2.4% Asian, and 4.3% another race. In-hospital mortality was higher in non-Caucasian groups. African American (adjusted odds ratio [aOR] 1.2; 95% confidence interval [CI]: 1.07-1.30; p &lt; .01) and another race (aOR 1.37; 95% CI: 1.15-1.63; p &lt; .01) had higher odds of mortality when compared with white women. African American (aOR 0.69; 95% CI: 0.62-0.72; p &lt; .01), Hispanics (aOR 0.81; 95% CI: 0.74-0.88; p &lt; .01), and Asian (aOR 0.79; 95% CI: 0.69-0.90; p &lt; .01) had lower odds of percutaneous intervention (PCI) when compared with whites. African Americans had fewer odds of Coronary Artery Bypass Graft (CABG) and use of Mechanical Circulatory Support (MCS) during the index admission. Non-Caucasians had more comorbidities, complications, and healthcare utilization costs. There are significant racial disparities in clinical outcomes and revascularization in female patients with STEMI. African American women have a higher likelihood of mortality among the different races. 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Previous studies showed that females with STEMI have higher mortality than men. There exist significant disparities in outcomes among women of different races presenting with STEMI. National inpatient sample (NIS) data was obtained from January 2016 to December 2018 for the hospitalization of female patients with STEMI. We compared outcomes, using an extensive multivariate regression analysis amongst women from different races. Our primary outcome was in-hospital mortality. Secondary outcomes were revascularization use, procedure complications, and healthcare utilization. Of 202 223 female patients with STEMI; 11.3% were African American, 7.4% Hispanic, 2.4% Asian, and 4.3% another race. In-hospital mortality was higher in non-Caucasian groups. African American (adjusted odds ratio [aOR] 1.2; 95% confidence interval [CI]: 1.07-1.30; p &lt; .01) and another race (aOR 1.37; 95% CI: 1.15-1.63; p &lt; .01) had higher odds of mortality when compared with white women. African American (aOR 0.69; 95% CI: 0.62-0.72; p &lt; .01), Hispanics (aOR 0.81; 95% CI: 0.74-0.88; p &lt; .01), and Asian (aOR 0.79; 95% CI: 0.69-0.90; p &lt; .01) had lower odds of percutaneous intervention (PCI) when compared with whites. African Americans had fewer odds of Coronary Artery Bypass Graft (CABG) and use of Mechanical Circulatory Support (MCS) during the index admission. Non-Caucasians had more comorbidities, complications, and healthcare utilization costs. There are significant racial disparities in clinical outcomes and revascularization in female patients with STEMI. African American women have a higher likelihood of mortality among the different races. 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subjects African Americans
Cardiac arrhythmia
Cardiovascular disease
Carotid arteries
Chronic obstructive pulmonary disease
Clinical Trial Result
Comorbidity
Females
Health services utilization
Heart attacks
Hispanic Americans
Hospitalization
Hospitals
Length of stay
Medicaid
Medicare
Minority & ethnic groups
Mortality
Patients
Population
Pulmonary arteries
Race
Regression analysis
Vein & artery diseases
Ventilators
White people
title Racial disparities in women with ST elevation myocardial infarction: A National Inpatient Sample review of baseline characteristics, co-morbidities, and outcomes in women with STEMI
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