Impact of dementia and drug compliance on patients with acute myocardial infarction

In South Korea, the number of people with dementia is rising at a worrisome rate, and many of them also have acute myocardial infarction (AMI), a disease with a high mortality rate. We speculated that dementia and drug compliance have significant impact on the mortality of patients with AMI. The stu...

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Published in:Clinical cardiology (Mahwah, N.J.) N.J.), 2023-10, Vol.46 (10), p.1253-1259
Main Authors: Lee, Wonjae, Kang, Si-Hyuck, Kim, Sun-Hwa, Lee, Seung-Yeon, Myung, Woojae, Jheon, Ki-Hyun, Yoon, Chang-Hwan, Suh, Jung-Won, Youn, Tae-Jin, Chae, In-Ho
Format: Article
Language:English
Subjects:
Aspirin
Beta blockers
Cardiovascular disease
Chronic obstructive pulmonary disease
Clinical Trial Result
Dementia
Diabetes
Enzymes
Heart attacks
Hypertension
Kidney diseases
Liver diseases
Medical prognosis
Metabolic disorders
Mortality
National health insurance
Older people
Patient compliance
Population
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Summary:In South Korea, the number of people with dementia is rising at a worrisome rate, and many of them also have acute myocardial infarction (AMI), a disease with a high mortality rate. We speculated that dementia and drug compliance have significant impact on the mortality of patients with AMI. The study derived data from the National Health Insurance Service-Senior for a retrospective cohort study. The total number of patients diagnosed with AMI for the first time between 2007 and 2013 was 16 835, among whom 2021 had dementia. Medication possession ratio (MPR) was used to assess medication adherence. AMI patients with dementia had unfavorable baseline characteristics; they had significantly higher risk of all-cause mortality (hazard ratio [HR]: 2.49; 95% confidence interval [CI]: 2.34-2.66; p 
ISSN:0160-9289
1932-8737
DOI:10.1002/clc.24091