Swallowing biomechanics in tracheostomised critically ill patients compared to age- and gender-matched healthy controls

The mechanistic effects of a tracheostomy on swallowing are unclear. Pharyngeal high-resolution manometry with impedance (P-HRM-I) is a novel swallow assessment tool providing quantifiable metrics. This study aimed to characterise swallowing biomechanics in tracheostomised critically ill (non-neurol...

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Published in:Critical care and resuscitation 2023-06, Vol.25 (2), p.97-105
Main Authors: Cheriyan, Sanith S., Schar, Mistyka S., Woods, Charmaine M., Bihari, Shailesh, Cock, Charles, Athanasiadis, Theodore, Omari, Taher I., Ooi, Eng H.
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Language:English
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Deglutition disorders
Intensive care unit
Manometry
Original
Tracheostomy
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creator Cheriyan, Sanith S.
Schar, Mistyka S.
Woods, Charmaine M.
Bihari, Shailesh
Cock, Charles
Athanasiadis, Theodore
Omari, Taher I.
Ooi, Eng H.
description The mechanistic effects of a tracheostomy on swallowing are unclear. Pharyngeal high-resolution manometry with impedance (P-HRM-I) is a novel swallow assessment tool providing quantifiable metrics. This study aimed to characterise swallowing biomechanics in tracheostomised critically ill (non-neurological) patients. Cohort study. Australian tertiary hospital intensive care unit. Tracheostomised adults, planned for decannulation. Swallowing assessment using P-HRM-I, compared to healthy age- and gender-matched controls. In this tracheostomised cohort (n = 10), the Swallow Risk Index, a global measure of swallow function, was significantly elevated (p 
doi_str_mv 10.1016/j.ccrj.2023.05.007
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Pharyngeal high-resolution manometry with impedance (P-HRM-I) is a novel swallow assessment tool providing quantifiable metrics. This study aimed to characterise swallowing biomechanics in tracheostomised critically ill (non-neurological) patients. Cohort study. Australian tertiary hospital intensive care unit. Tracheostomised adults, planned for decannulation. Swallowing assessment using P-HRM-I, compared to healthy age- and gender-matched controls. In this tracheostomised cohort (n = 10), the Swallow Risk Index, a global measure of swallow function, was significantly elevated (p &lt; 0.001). At the upper oesophageal sphincter (UOS), hypopharyngeal intrabolus pressure and UOS integrated relaxation pressure were significantly elevated (control 0.65 mmHg [-1.02, 2.33] v tracheostomy 13.7 mmHg [10.4, 16.9], P &lt; 0.001; control −4.28 mmHg [-5.87, 2.69] v tracheostomy 12.2 mmHg [8.83, 15.6], P &lt; 0.001, respectively). Furthermore, UOS opening extent and relaxation time were reduced (control 4.83 mS [4.60, 5.07] v tracheostomy 4.33 mS [3.97, 4.69], P = 0.002; control 0.52 s [0.49, 0.55] v tracheostomy 0.41 s [0.37, 0.45], P &lt; 0.001, respectively). Total pharyngeal contractility (PhCI) measuring pharyngeal pressure generation was significantly elevated (control 199.5 mmHg cm.s [177.4, 221.6] v tracheostomy 326.5 mmHg cm.s [253.3, 399.7]; P = 0.001). In a critically ill tracheostomised cohort, UOS dysfunction was the prevalent biomechanical feature, with elevated pharyngeal pressures. Pharyngeal weakness is not contributing to dysphagia in this cohort. Instead, elevated pharyngeal pressures may represent a compensatory mechanism to overcome the UOS dysfunction. 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subjects Deglutition disorders
Intensive care unit
Manometry
Original
Tracheostomy
title Swallowing biomechanics in tracheostomised critically ill patients compared to age- and gender-matched healthy controls
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