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O029 Clinical features and outcomes of patients referred to a Respiratory Failure service

Abstract Non-invasive ventilation (NIV) improves quality of life and mortality in patients with hypercapnic respiratory failure. We reviewed the last decade of long-term home NIV provision in a single centre via an observational retrospective study. Data were prospectively collected in a database. A...

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Bibliographic Details
Published in:Sleep advances. 2023-10, Vol.4 (Supplement_1), p.A10-A11
Main Authors: Moore, E, Howard, L, Wheatley, J, Falland, K, Chien, J, Wu, P, Kairaitis, K
Format: Article
Language:English
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Summary:Abstract Non-invasive ventilation (NIV) improves quality of life and mortality in patients with hypercapnic respiratory failure. We reviewed the last decade of long-term home NIV provision in a single centre via an observational retrospective study. Data were prospectively collected in a database. Anthropometric and demographic data were expressed as mean±SD. Indications for chronic home NIV were categorised into: neuromuscular diseases (NMD) [including motor neuron disease (MND)]; obstructive sleep apnoea/obesity hypoventilation (OSA/OHS); pulmonary disease; and others. Linear regression analysis was performed for the annual incidence by indication, and multivariate Cox regression performed compares MND mortality with other causes. 541 new patients (Age 60.8 ±17.1 years; 273 Female; BMI 33.4±13.9 kg/m2 (n=380)) were commenced on NIV between 2012-2022. Patient numbers increased by 2.3 (0.4-4.1) per year (slope, (95% confidence intervals); p
ISSN:2632-5012
2632-5012
DOI:10.1093/sleepadvances/zpad035.029